AIMC Topic: Depressive Disorder, Major

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Refining Prediction in Treatment-Resistant Depression: Results of Machine Learning Analyses in the TRD III Sample.

The Journal of clinical psychiatry
OBJECTIVE: The study objective was to generate a prediction model for treatment-resistant depression (TRD) using machine learning featuring a large set of 47 clinical and sociodemographic predictors of treatment outcome.

Differential privacy-based evaporative cooling feature selection and classification with relief-F and random forests.

Bioinformatics (Oxford, England)
MOTIVATION: Classification of individuals into disease or clinical categories from high-dimensional biological data with low prediction error is an important challenge of statistical learning in bioinformatics. Feature selection can improve classific...

A clinical perspective on the relevance of research domain criteria in electronic health records.

The American journal of psychiatry
OBJECTIVE: The limitations of the DSM nosology for capturing dimensionality and overlap in psychiatric syndromes, and its poor correspondence to underlying neurobiology, have been well established. The Research Domain Criteria (RDoC), a proposed dime...