AIMC Topic: DNA, Neoplasm

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Machine learning-based integrative analysis of methylome and transcriptome identifies novel prognostic DNA methylation signature in uveal melanoma.

Briefings in bioinformatics Jul 20, 2021
Uveal melanoma (UVM) is the most common primary intraocular human malignancy with a high mortality rate. Aberrant DNA methylation has rapidly emerged as a diagnostic and prognostic signature in many cancers. However, such DNA methylation signature av...
Female Melanoma Humans Machine Learning Neoplasm Proteins Predictive Value of Tests Gene Expression Regulation, Neoplastic DNA Methylation Uveal Neoplasms Uveal Melanoma Disease-Free Survival DNA, Neoplasm Male Middle Aged Gene Expression Profiling Transcriptome Adult Survival Rate Aged Aged, 80 and over
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Clinical applications of artificial intelligence in urologic oncology.

Current opinion in urology Nov 1, 2020
PURPOSE OF REVIEW: This review aims to shed light on recent applications of artificial intelligence in urologic oncology.
Urology Urogenital Neoplasms Genomics DNA, Neoplasm Humans Artificial Intelligence Algorithms Biomarkers, Tumor
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Antiproliferative and Apoptotic Activities of the Medicinal Mushroom Phellinus rimosus (Agaricomycetes) on HCT116 Human Colorectal Carcinoma Cells.

International journal of medicinal mushrooms Jan 1, 2018
Phellinus rimosus is a host-specific wood-rotting polypore that has been reported to be used by some tribes in Kerala, India, for curing mumps. We isolated a novel polysaccharide-protein complex from Ph. rimosus (PPC-Pr) that possessed significant an...
Humans Cell Proliferation DNA Fragmentation Basidiomycota Antineoplastic Agents Apoptosis HCT116 Cells DNA, Neoplasm
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HUMAN DNA QUANTIFICATION IN THE STOOLS OF PATIENTS WITH COLORECTAL CANCER.

Arquivos de gastroenterologia Dec 1, 2015
BACKGROUND: Colorectal cancer is one of the main cause of cancer in the world. Colonoscopy is the best screen method, however the compliance is less than 50%. Quantification of human DNA (hDNA) in the feces may be a possible screen non-invasive metho...
Polymerase Chain Reaction DNA, Neoplasm ROC Curve Neoplasm Staging Case-Control Studies Feces Reproducibility of Results Sensitivity and Specificity Humans Female Male Colonoscopy Colorectal Neoplasms Biomarkers, Tumor
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Machine learning from concept to clinic: reliable detection of BRAF V600E DNA mutations in thyroid nodules using high-dimensional RNA expression data.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing Jan 1, 2015
The promise of personalized medicine will require rigorously validated molecular diagnostics developed on minimally invasive, clinically relevant samples. Measurement of DNA mutations is increasingly common in clinical settings but only higher-preval...
Proto-Oncogene Proteins B-raf RNA, Neoplasm DNA, Neoplasm Oligonucleotide Array Sequence Analysis Humans Machine Learning Mutation Computational Biology Gene Expression Profiling High-Throughput Nucleotide Sequencing Support Vector Machine DNA Mutational Analysis Thyroid Nodule Biopsy, Fine-Needle
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