Mathematical models are conventionally used to understand the of tumor behaviors, but they generally lack in precisely correlating drug efficacy with tumor response. Artificial intelligence (AI) has forged a new avenue in cancer management, but requi...
Confined spaces in the human body pose substantial challenges for biomedical procedures. Navigating these ultrasmall environments is essential for precise drug delivery, improving treatment outcomes and reducing adverse effects. Microrobots offer a p...
Poly(lactide-co-glycolide) (PLGA) nanoparticles are promising drug delivery systems, widely recognized for their ability to overcome various limitations associated with conventional formulations. However, designing and optimizing such formulations is...
The blood-brain barrier (BBB) poses a major challenge to the effective delivery of therapeutic agents for the treatment of central nervous system (CNS) disorders. The integration of cell membrane engineering with nanotechnology has recently enabled t...
A combined methodology was performed based on chemometrics and machine learning regressive models in estimation of polysaccharide-coated colonic drug delivery. The release of medication was measured using Raman spectroscopy and the data was used for ...
This study employed multiple machine learning (ML) methods to model and predict key attributes of PLGA nanoparticles, specifically particle size and zeta potential. The predictions were based on input variables, including PLGA polymer type, PLGA conc...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Jun 27, 2025
Electrospinning increases opportunities to facilitate the production of drug delivery systems (DDSs), such as complex biomaterials. However, the manual measurement of fiber diameters remains a critical bottleneck, hindering efficiency and scalability...
International journal of pharmaceutics
Jun 25, 2025
Polymer microparticles (MPs) have long been a cornerstone of long-acting injectable (LAI) drug delivery, offering controlled drug release, reduced dosing frequency, and improved patient adherence. Among these, poly(lactide-co-glycolide) (PLGA)-based ...
Biochemical and biophysical research communications
Jun 25, 2025
Next-generation cancer nanomedicines are revolutionizing therapeutic precision through multifunctional, adaptive, and tumor-specific strategies. This review discusses emerging innovations in cancer nanomedicine, including stimuli-responsive nanomedic...
This study aims to optimize ibuprofen-based Drug Delivery Systems (DDSs) to address their short half-life and enhance controlled release. Advanced machine learning techniques, including Artificial Neural Networks, Random Forest, and CatBoost, were em...
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