International journal of chronic obstructive pulmonary disease
May 6, 2025
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly increase morbidity, mortality, and healthcare costs, posing a significant burden on the management o...
Lung cancer has been stated as one of the prevalent killers of cancer up to this present time and this clearly underlines the rationale for early diagnosis to enhance life expectancy of patients afflicted with the condition. The reasons behind the us...
BACKGROUND: Cancer is a life-threatening disease and a leading cause of death worldwide, with an estimated 611,000 deaths and over 2 million new cases in the United States in 2024. The rising incidence of major cancers, including among younger indivi...
The British journal of general practice : the journal of the Royal College of General Practitioners
May 2, 2025
BACKGROUND: The journey of >80% of patients diagnosed with lung cancer starts in general practice. About 75% of patients are diagnosed when it is at an advanced stage (3 or 4), leading to >80% mortality within 1 year at present. The long-term data in...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
May 1, 2025
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC), known for its high fatality rate, is often diagnosed in its advanced stages where surgical options are not viable. This highlights the critical need for innovative and effective early detection techni...
The lack of reliable non-invasive biomarkers for early colorectal cancer (CRC) diagnosis underscores the need for improved diagnostic tools. Extracellular vesicles (EVs) have emerged as promising candidates for liquid-biopsy-based cancer monitoring. ...
The Journal of molecular diagnostics : JMD
Apr 29, 2025
Recent studies highlight the promise of blood-based multicancer early detection (MCED) tests for identifying asymptomatic patients with cancer. However, most focus on a single cancer hallmark, thus limiting effectiveness because of cancer's heterogen...
In existing breast cancer prediction research, most models rely solely on a single type of imaging data, which limits their performance. To overcome this limitation, the present study explores breast cancer prediction models based on multimodal medic...
European journal of nuclear medicine and molecular imaging
Apr 25, 2025
PURPOSE: To assess feasibility of lung cancer screening, we analysed lung lesion detectability simulating low-dose and convolutional neural network (CNN) denoised [F]-FDG PET/CT reconstructions.
Despite the strides made in medical science, pancreatic cancer continues to be a threat, highlighting the urgent need for creative strategies to address this concern. Recently, a potential approach that has attracted significant attention is using ma...
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