AIMC Topic: Environmental Exposure

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Long-term exposure to ambient air pollution and cardiometabolic multimorbidity in Chinese adults over 45 years.

Scientific reports
The rising prevalence of cardiometabolic multimorbidity (CMM), characterized by the coexistence of two or more cardiometabolic disorders, poses a significant public health challenge in aging populations. While ambient air pollution is a recognized en...

Ischemic heart disease mortality due to fine particulate matter in Seoul between 2016 and 2020.

BMC public health
BACKGROUND: Ischemic heart disease (IHD) continues to rank among the leading global causes of mortality, consistently linked to long-term exposure to fine particulate matter (PM). Despite a declining trend in the annual average PM concentration in Se...

Association between exposure to PM and black carbon and the risk of childhood leukemia in Tehran: A case-control study with critical exposure time windows.

Environmental research
Limited research has explored the relationship between air pollutants and childhood leukemia during critical exposure periods, and no such research has been conducted in Tehran to date. This study assessed the association between exposure to fine par...

DEHP promotes psoriasis via immune modulation and direct molecular interactions: Evidence from epidemiology, multi-omics, and structural simulation.

The Science of the total environment
Di (2-ethylhexyl) phthalate (DEHP), a widely used plasticizer with known immunotoxic effects, has been suspected of aggravating inflammatory skin conditions, yet its role in autoimmune diseases such as psoriasis remains poorly defined. In this study,...

Methods and Uncertainty in Predictions of Arsenic Exposure and Health Outcomes for Private Well Users in Massachusetts.

Environmental science & technology
In the United States, most people get their drinking water from public water systems, whose quality is regulated by the Safe Drinking Water Act; however, an estimated 40 million people rely on unregulated private wells. In Massachusetts ∼500,000 peop...

Chemically Labeled Exposome Analysis (CLEAN): A Strategy for Nontargeted Identification of Urinary Metabolites.

Environmental science & technology
Urinary exposome analysis faces analytical challenges due to the lack of reference standards for biotransformed products and the wide structural diversity of metabolites. This study developed a chemically labeled exposome analysis (CLEAN) strategy fo...

Harnessing Geospatial Artificial Intelligence (GeoAI) for Environmental Epidemiology: A Narrative Review.

Current environmental health reports
PURPOSE OF REVIEW: Geospatial analysis is an essential tool for research on the role of environmental exposures and health, and critical for understanding impacts of environmental risk factors on diseases with long latency (e.g. cardiovascular diseas...

From disinfectant to neurodegeneration: Integrating machine learning and mendelian randomization reveals triclosan as a novel environmental risk factor for Alzheimer's disease.

Environmental pollution (Barking, Essex : 1987)
This study systematically investigated the association between triclosan (TCS) exposure and Alzheimer's disease (AD) risk via integrated bioinformatics approaches. TCS-AD-related genes were identified using bioinformatics tools and public databases, ...

Using Environmental Mixture Exposure-Triggered Biological Knowledge-Driven Machine Learning to Predict Early Pregnancy Loss.

Environmental science & technology
The assessment of how environmental mixture exposures affect reproductive health faces difficulties. While knowledge graph networks offer valuable advantages in biological interpretation and prediction, their application in epidemiological studies, p...