AIMC Topic: Fluorine Radioisotopes

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Automated radiosynthesis of [(18)F]ciprofloxacin.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
We transferred the previously published manual synthesis of [(18)F]ciprofloxacin (decay-corrected RCY: 5.5±1.0%) to an automated synthesis module (TRACERlab(TM) FXFDG, GE Healthcare) and observed a strong decrease in RCY (0.4±0.4%). When replacing th...

Evaluating Automated Tools for Lesion Detection on F Fluoroestradiol PET/CT Images and Assessment of Concordance with Standard-of-Care Imaging in Metastatic Breast Cancer.

Radiology. Imaging cancer
Purpose To evaluate two automated tools for detecting lesions on fluorine 18 (F) fluoroestradiol (FES) PET/CT images and assess concordance of F-FES PET/CT with standard diagnostic CT and/or F fluorodeoxyglucose (FDG) PET/CT in patients with breast c...

Potential Applications of Artificial Intelligence and Machine Learning in Radiochemistry and Radiochemical Engineering.

PET clinics
Artificial intelligence and machine learning are poised to disrupt PET imaging from bench to clinic. In this perspective, the authors offer insights into how the technology could be applied to improve the radiosynthesis of new radiopharmaceuticals fo...