AIMC Topic: Forensic Genetics

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Predicting haplogroups using a versatile machine learning program (PredYMaLe) on a new mutationally balanced 32 Y-STR multiplex (CombYplex): Unlocking the full potential of the human STR mutation rate spectrum to estimate forensic parameters.

Forensic science international. Genetics Jun 29, 2020
We developed a new mutationally well-balanced 32 Y-STR multiplex (CombYplex) together with a machine learning (ML) program PredYMaLe to assess the impact of STR mutability on haplogourp prediction, while respecting forensic community criteria (high D...
Male Multiplex Polymerase Chain Reaction Polymorphism, Single Nucleotide Humans Machine Learning Microsatellite Repeats Forensic Genetics DNA Fingerprinting Haplotypes Mutation Rate Chromosomes, Human, Y
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Forensic STR allele extraction using a machine learning paradigm.

Forensic science international. Genetics Oct 28, 2019
We present a machine learning approach to short tandem repeat (STR) sequence detection and extraction from massively parallel sequencing data called Fragsifier. Using this approach, STRs are detected on each read by first locating the longest repeat ...
DNA Fingerprinting High-Throughput Nucleotide Sequencing Machine Learning Humans Microsatellite Repeats Algorithms Alleles Genotype Forensic Genetics Genetic Loci Electrophoresis, Capillary
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Artificially intelligent scoring and classification engine for forensic identification.

Forensic science international. Genetics Sep 19, 2019
Despite advances in genotyping technologies, traditional kinship analysis tools utilized in forensic identification have seen limited evolution and lack measures of accuracy. Here, we leverage artificial intelligence (AI) and extend the Elston-Stewar...
Humans Artificial Intelligence Pedigree Likelihood Functions Microsatellite Repeats Algorithms Logistic Models Datasets as Topic Forensic Genetics DNA Fingerprinting
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Novel taxonomy-independent deep learning microbiome approach allows for accurate classification of different forensically relevant human epithelial materials.

Forensic science international. Genetics Apr 4, 2019
Correct identification of different human epithelial materials such as from skin, saliva and vaginal origin is relevant in forensic casework as it provides crucial information for crime reconstruction. However, the overlap in human cell type composit...
Forensic Genetics Microbiota High-Throughput Nucleotide Sequencing Vagina Male Deep Learning Sequence Analysis, RNA RNA, Ribosomal, 16S Skin Humans Saliva Female
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CaseSolver: An investigative open source expert system based on EuroForMix.

Forensic science international. Genetics Apr 2, 2019
For very serious crimes, reporting scientists often have to contend with complex cases where literally hundreds of items are submitted by investigators for analysis. In order to efficiently expedite the challenge of comparing reference profiles to ev...
DNA Fingerprinting Microsatellite Repeats Forensic Genetics Humans Software Expert Systems Gene Frequency Likelihood Functions Databases, Nucleic Acid
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The generalisability of artificial neural networks used to classify electrophoretic data produced under different conditions.

Forensic science international. Genetics Nov 2, 2018
Previous work has shown that artificial neural networks can be used to classify signal in an electropherogram into categories that have interpretational meaning (such as allele, baseline, pull-up or stutter). The previous work trained the neural netw...
Electrophoresis Humans Datasets as Topic Neural Networks, Computer Forensic Genetics
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An artificial neural network system to identify alleles in reference electropherograms.

Forensic science international. Genetics Jul 8, 2017
Electropherograms are produced in great numbers in forensic DNA laboratories as part of everyday criminal casework. Before the results of these electropherograms can be used they must be scrutinised by analysts to determine what the identified data t...
Humans Neural Networks, Computer Algorithms Alleles Electrophoresis Forensic Genetics DNA Fingerprinting
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DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing.

Forensic science international. Genetics Feb 28, 2017
The ability to estimate the age of the donor from recovered biological material at a crime scene can be of substantial value in forensic investigations. Aging can be complex and is associated with various molecular modifications in cells that accumul...
CpG Islands Humans Forensic Genetics Neural Networks, Computer Twins, Monozygotic Middle Aged Aged Machine Learning DNA Adult Epigenomics Aging Saliva DNA Methylation High-Throughput Nucleotide Sequencing
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Teaching artificial intelligence to read electropherograms.

Forensic science international. Genetics Jul 28, 2016
Electropherograms are produced in great numbers in forensic DNA laboratories as part of everyday criminal casework. Before the results of these electropherograms can be used they must be scrutinised by analysts to determine what the identified data t...
Microsatellite Repeats Humans Forensic Genetics DNA Fingerprinting Neural Networks, Computer Laboratories Artificial Intelligence Electrophoresis Artifacts
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Internal validation of the QIAamp DNA Investigator Kit, QIAamp 96 DNA Swab BioRobot Kit and the BioRobot Universal System for DNA extraction from reference and crime scene samples.

Forensic science international. Genetics Nov 1, 2014
DNA Humans Robotics Specimen Handling Forensic Genetics
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