AIMC Topic: Glycosaminoglycans
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The Use of Quantitative Digital Pathology to Measure Proteoglycan and Glycosaminoglycan Expression and Accumulation in Healthy and Diseased Tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Sep 16, 2020
Advances in reagents, methodologies, analytic platforms, and tools have resulted in a dramatic transformation of the research pathology laboratory. These advances have increased our ability to efficiently generate substantial volumes of data on the e...
Sulodexide modulates the dialysate effect on the peritoneal mesothelium.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Mar 20, 2020
Peritoneal membrane damage during chronic peritoneal dialysis is the main cause of that treatment failure. Preservation of the mesothelial cells (MC) is important for the survival of the peritoneum. Evaluation of dialysates effect on the function of ...
Biochemical, machine learning and molecular approaches for the differential diagnosis of Mucopolysaccharidoses.
Molecular and cellular biochemistry
Mar 21, 2019
This study was aimed to construct classification and regression tree (CART) model of glycosaminoglycans (GAGs) for the differential diagnosis of Mucopolysaccharidoses (MPS). Two-dimensional electrophoresis and liquid chromatography-tandem mass spectr...
Glycosaminoglycan levels in dried blood spots of patients with mucopolysaccharidoses and mucolipidoses.
Molecular genetics and metabolism
Dec 22, 2016
UNLABELLED: Mucopolysaccharidoses (MPSs) and mucolipidoses (ML) are groups of lysosomal storage disorders in which lysosomal hydrolases are deficient leading to accumulation of undegraded glycosaminoglycans (GAGs), throughout the body, subsequently r...
Infant
Adolescent
Child, Preschool
Child
Age Factors
Humans
Dried Blood Spot Testing
Adult
Female
Heparitin Sulfate
Dermatan Sulfate
Sensitivity and Specificity
Chromatography, Liquid
Mucopolysaccharidoses
Infant, Newborn
Keratan Sulfate
Glycosaminoglycans
Tandem Mass Spectrometry
Male
Mucolipidoses
Young Adult
Non-destructive assessment of tissue engineered cartilage maturity using visible and near infrared spectroscopy combined with machine learning.
Biosensors & bioelectronics
Oct 15, 2025
Tissue engineering is a promising approach to address the unmet clinical need for treating cartilage damage. Monitoring the characteristics of tissue-engineered cartilage constructs (TECs) during culture is critical for optimizing culture conditions ...
When Simulations Meet Machine Learning: Redefining Molecular Docking for Protein-Glycosaminoglycan Systems.
Journal of computational chemistry
Jun 30, 2025
Glycosaminoglycans (GAGs) are linear, negatively charged carbohydrates that modulate enzymatic activity in the extracellular matrix. Their high flexibility and specificity in protein-GAG interactions pose challenges for both experimental and computat...
The effect of glycosaminoglycans, extracted from the skin of tilapia, in the sperm freezing medium of Colossoma macropomum.
Cryo letters
Jan 1, 2021
BACKGROUND: Sulfated polysaccharides from the skin of Nile tilapia (Oreochromis niloticus), added to the tambaqui (Colossoma macropomum) semen diluting medium, can be potential antioxidants and promote the maintenance of sperm quality.
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