AIMC Topic: Gold

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Ultrasensitive Detection of Circulating Plasma Cells Using Surface-Enhanced Raman Spectroscopy and Machine Learning for Multiple Myeloma Monitoring.

Analytical chemistry
Multiple myeloma is a hematologic malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Despite therapeutic advancements, there remains a critical need for reliable, noninvasive methods to monitor multiple myeloma...

Bacterial Wastewater-Based Epidemiology Using Surface-Enhanced Raman Spectroscopy and Machine Learning.

Nano letters
Although wastewater-based epidemiology has been used extensively for the surveillance of viral diseases, it has not been used to a similar extent for bacterial diseases. This is in part owing to difficulties in distinguishing pathogenic from nonpatho...

Radial SERS acquisition on coffee ring for Serum-based breast cancer diagnosis through Multilayer Perceptron.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The coffee-ring effect, involving spontaneous solute separation, has demonstrated promising potential in the context of patient serum analysis. In this study, an approach leveraging the coffee-ring-based analyte redistribution was developed for spect...

Identification of Phosphodiesterase type 5 inhibitors (PDE5is) analogues using surface-enhanced Raman scattering and machine learning algorithm.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Phosphodiesterase type 5 inhibitors (PDE5is), primarily used for the treatment of erectile dysfunction, have been severely misused in recent years, posing a threat to public health and safety. This study developed a method that combines Surface-enhan...

Freeze-Thaw-Induced Patterning of Extracellular Vesicles with Artificial Intelligence for Breast Cancers Identifications.

Small (Weinheim an der Bergstrasse, Germany)
Extracellular vesicles (EVs) play a crucial role in the occurrence and progression of cancer. The efficient isolation and analysis of EVs for early cancer diagnosis and prognosis have gained significant attention. In this study, for the first time, a...

Early colorectal cancer detection: a serum analysis platform combining SERS and machine learning.

Analytical methods : advancing methods and applications
Colorectal cancer (CRC) is one of the deadliest malignancies globally, with high incidence and mortality rates. Early detection is crucial for improving treatment success rates and patient survival. However, due to the difficulty in detecting early s...

Bacteriophage-Activated DNAzyme Hydrogels Combined with Machine Learning Enable Point-of-Use Colorimetric Detection of Escherichia coli.

Advanced materials (Deerfield Beach, Fla.)
Developing cost-effective, consumer-accessible platforms for point-of-use environmental and clinical pathogen testing is a priority, to reduce reliance on laborious, time-consuming culturing approaches. Unfortunately, a system offering ultrasensitive...

Machine learning-assisted SERS sensor for fast and ultrasensitive analysis of multiplex hazardous dyes in natural products.

Journal of hazardous materials
The adulteration of natural products with multiple azo dyes has become a serious public health concern. Thus, on-site trace additive detection is demanded. Herein, we developed a gold-nanorod-based surface-enhanced Raman scattering (SERS) sensor to d...

Deep learning-assisted surface-enhanced Raman spectroscopy detection of intracellular reactive oxygen species.

Talanta
Realizing the intelligent analysis of the intracellular reactive oxygen species (ROS) is beneficial to quick diagnosis of diseases. Herein, surface-enhanced Raman spectroscopy (SERS) technology was combined with deep learning to establish a smart det...

Plasma treated bimetallic nanofibers as sensitive SERS platform and deep learning model for detection and classification of antibiotics.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Design of a sensitive, cost-effective SERS substrate is critical for probing analyte in trace concentration in real field environment. Present work reports the fabrication of an oxygen (O) plasma treated bimetallic nanofibers as a sensitive SERS plat...