AIMC Topic: Guanosine

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GenoM7GNet: An Efficient N-Methylguanosine Site Prediction Approach Based on a Nucleotide Language Model.

IEEE/ACM transactions on computational biology and bioinformatics Dec 10, 2024
N-methylguanosine (m7G), one of the mainstream post-transcriptional RNA modifications, occupies an exceedingly significant place in medical treatments. However, classic approaches for identifying m7G sites are costly both in time and equipment. Meanw...
Humans Algorithms Deep Learning Neural Networks, Computer Sequence Analysis, RNA RNA Computational Biology Guanosine
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Moss-m7G: A Motif-Based Interpretable Deep Learning Method for RNA N7-Methlguanosine Site Prediction.

Journal of chemical information and modeling Jul 16, 2024
N-7methylguanosine (m7G) modification plays a crucial role in various biological processes and is closely associated with the development and progression of many cancers. Accurate identification of m7G modification sites is essential for understandin...
Nucleotide Motifs Guanosine Deep Learning RNA
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THRONE: A New Approach for Accurate Prediction of Human RNA N7-Methylguanosine Sites.

Journal of molecular biology Mar 16, 2022
N-methylguanosine (m7G) is an essential, ubiquitous, and positively charged modification at the 5' cap of eukaryotic mRNA, modulating its export, translation, and splicing processes. Although several machine learning (ML)-based computational predicto...
Machine Learning Software Humans Genome, Human Guanosine Sequence Analysis, RNA Computational Biology RNA Caps
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Identifying N7-methylguanosine sites by integrating multiple features.

Biopolymers Oct 28, 2021
Recent studies reported that N7-methylguanosine (m7G) plays a vital role in gene expression regulation. As a consequence, determining the distribution of m7G is a crucial step towards further understanding its biological functions. Although biologica...
Support Vector Machine Guanosine RNA Algorithms
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m7GPredictor: An improved machine learning-based model for predicting internal m7G modifications using sequence properties.

Analytical biochemistry Aug 14, 2020
As one of the most important post-transcriptional modifications, the N7-methylguanosine (m7G) plays a key role in many RNA processing events. The accurate identification of m7G is crucial for elucidating its biological significance and future applica...
Models, Theoretical Databases, Genetic Support Vector Machine User-Computer Interface ROC Curve Machine Learning Guanosine Area Under Curve
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Iterative feature representation algorithm to improve the predictive performance of N7-methylguanosine sites.

Briefings in bioinformatics Jul 20, 2021
MOTIVATION: N7-methylguanosine (m7G) is an important epigenetic modification, playing an essential role in gene expression regulation. Therefore, accurate identification of m7G modifications will facilitate revealing and in-depth understanding their ...
Guanosine HeLa Cells Support Vector Machine Humans DNA Methylation Hep G2 Cells Epigenesis, Genetic
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[Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials Nov 1, 2015
OBJECTIVE: To establish a method for simultaneous determination of nucleosides and nucleobases in natural, cultured and tissue culture Anoectochilus roxburghii by high performance liquid chromatography-electrospray ionization/ion trap mass spectromet...
Adenine Adenosine Uridine Guanosine Nucleosides Hypoxanthine Chromatography, Liquid Orchidaceae Uracil Nucleotides Mass Spectrometry Drugs, Chinese Herbal
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