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Hypoxanthine

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[Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
OBJECTIVE: To establish a method for simultaneous determination of nucleosides and nucleobases in natural, cultured and tissue culture Anoectochilus roxburghii by high performance liquid chromatography-electrospray ionization/ion trap mass spectromet...

Maternal and umbilical cord plasma purine concentrations after oral carbohydrate loading prior to elective Cesarean delivery under spinal anesthesia: a randomized controlled trial.

BMC pregnancy and childbirth
OBJECTIVE: To evaluate the effect of preoperative intake of oral carbohydrates versus standard preoperative fasting prior to elective cesarean delivery on plasma purine levels (hypoxanthine, xanthine, and uric acid) and beta-hydroxybutyrate (β-HB) in...

Metabolomics Unveils Disrupted Pathways in Parkinson's Disease: Toward Biomarker-Based Diagnosis.

ACS chemical neuroscience
Parkinson's disease (PD) is a neurodegenerative disorder characterized by diverse symptoms, where accurate diagnosis remains challenging. Traditional clinical observation methods often result in misdiagnosis, highlighting the need for biomarker-based...

Simultaneous quantitative analysis of multiple metabolites using label-free surface-enhanced Raman spectroscopy and explainable deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Metabolites serve as vital biomarkers, reflecting physiological and pathological states and offering insights into disease progression and early detection. This study introduces an advanced analytical technique integrating label-free Surface-Enhanced...