Heart failure (HF) is a complex and prevalent condition, particularly in the elderly, presenting symptoms like chest tightness, shortness of breath, and dyspnea. The study aimed to improve the classification of HF subtypes and identify potential drug...
AIMS: Mortality risk after hospitalization for heart failure (HF) is high, especially in the first 90 days. This study aimed to construct a model automatically predicting 90 day post-discharge mortality using electronic health record (EHR) data 48 h ...
International journal of biological macromolecules
Feb 11, 2025
The purpose of this study was to investigate the molecular structure of NRG-1 protein and its mechanism of action in adult hypertensive heart failure. The amino acid sequence of NRG-1 protein was analyzed by bioinformatics method. High-throughput seq...
International journal of biological macromolecules
Feb 8, 2025
Oxidative stress (OS) is a pivotal mechanism driving the progression of cardiovascular diseases, particularly heart failure (HF). However, the comprehensive characterisation of OS-related genes in HF remains largely unexplored. In the present study, ...
Biochimica et biophysica acta. Molecular basis of disease
Feb 4, 2025
BACKGROUND: Despite maximal pharmacological treatment guided by clinical guidelines, the prognosis of heart failure (HF) remains poor, posing a significant public health burden. This necessitates uncovering novel pathological and cardioprotective pat...
INTRODUCTION: AI-based ECG has shown good accuracy in diagnosing heart failure. However, due to the heterogeneity of studies regarding cutoff points, its precision for specifically detecting heart failure with left ventricle reduced ejection fraction...
Accurate identification of individuals at high risk for mild cognitive impairment (MCI) among chronic heart failure (CHF) patients is crucial for reducing rehospitalization and mortality rates. This study aimed to develop and validate a machine learn...
Heart failure is a leading cause of premature death, especially among individuals with a sedentary lifestyle. Early and accurate detection is essential to prevent the progression of this situation. However, many existing prediction systems failed to ...
BACKGROUND: Chronic heart failure (CHF) is a serious threat to human health, with high morbidity and mortality rates, imposing a heavy burden on the health care system and society. With the abundance of medical data and the rapid development of machi...
European journal of internal medicine
Jan 28, 2025
BACKGROUND: Assessing the relative performance of machine learning (ML) methods and conventional statistical methods in predicting prognosis in heart failure (HF) still remains a challenging research field.
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