AI Medical Compendium Topic

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Herpesvirus 1, Human

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Alantolactone exhibited anti-herpes simplex virus 1 (HSV-1) action in vitro.

Bioscience trends
The aim of this study was to determine the inhibitory action of alantolactone, a gradient of traditional Chinese medicine Inulae Radix (Tu-Mu-Xiang), on herpes simplex virus 1 (HSV-1). African green monkey kidney cells (Vero cells) were infected with...

Experimental Data Based Machine Learning Classification Models with Predictive Ability to Select in Vitro Active Antiviral and Non-Toxic Essential Oils.

Molecules (Basel, Switzerland)
In the last decade essential oils have attracted scientists with a constant increase rate of more than 7% as witnessed by almost 5000 articles. Among the prominent studies essential oils are investigated as antibacterial agents alone or in combinatio...

DeepVISP: Deep Learning for Virus Site Integration Prediction and Motif Discovery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Approximately 15% of human cancers are estimated to be attributed to viruses. Virus sequences can be integrated into the host genome, leading to genomic instability and carcinogenesis. Here, a new deep convolutional neural network (CNN) model is deve...

Combination therapy synergism prediction for virus treatment using machine learning models.

PloS one
Combining different drugs synergistically is an essential aspect of developing effective treatments. Although there is a plethora of research on computational prediction for new combination therapies, there is limited to no research on combination th...

Deep learning-based image classification reveals heterogeneous execution of cell death fates during viral infection.

Molecular biology of the cell
Cell fate decisions, such as proliferation, differentiation, and death, are driven by complex molecular interactions and signaling cascades. While significant progress has been made in understanding the molecular determinants of these processes, hist...