AIMC Topic: HIV Infections

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Candidate correlates of protection in the HVTN505 HIV-1 vaccine efficacy trial identified by positive-unlabeled learning.

PLoS computational biology
With a goal of unveiling mechanisms by which vaccines can provide protection against HIV-1 acquisition, several studies have explored correlates of risk of HIV-1 acquisition in HVTN 505, which was a phase IIb trial conducted to assess the safety and ...

Anxiety responses and testing intentions among gay and bisexual men using an AI-powered HIV/STI risk assessment tool: a quasi-experimental study.

BMC public health
INTRODUCTION: Web-based tools for the assessment of the risk of sexually transmitted infections (STI) may increase testing but also may induce anxiety. We evaluated anxiety responses and testing intentions among gay, bisexual and other men who have s...

Explainable machine learning for predicting clinical outcomes in HIV/TB co-infection: a comparative retrospective study.

BMC infectious diseases
BACKGROUND: HIV/TB co-infection presents substantial public-health challenges, showing greater treatment-failure and mortality rates than tuberculosis alone. Recent advances in machine learning (ML) provide a robust means of identifying high-risk pat...

Formulation and validation of a regional household wealth index for sub-Saharan Africa.

PloS one
A new era in global health assistance requires a focus on efficiently using limited and declining donor funds. This shift requires better evaluation methods to allocate resources effectively. Most evaluations in low- and middle-income countries (LMIC...

Multilingual voice-enabled informatics tools: Catalyst for equitable AI in HIV and HIV-comorbidity healthcare management.

PloS one
Human Immunodeficiency Virus (henceforth HIV) is a global health problem, presently with no known cure. Africa has one of the highest incidences of HIV. Nigeria, within the West African (WA) region, is one of the largest economies on the continent. H...

Prevalence and factors associated with HIV drug resistance among adult persons living with HIV/AIDS in nine countries of Sub-Saharan Africa using population-based HIV impact assessments: 2015-2019.

BMC public health
INTRODUCTION: HIV drug resistance (HIVDR) remains a significant challenge in sub-Saharan Africa (SSA) due to limited effective Treatment and healthcare resources vary. Using the first widely available HIVDR surveillance data in SSA, we calculated the...

Predicting malnutrition in PLWHIV using machine learning in gondar, Ethiopia.

BMC public health
BACKGROUND: Human Immunodeficiency Virus (HIV) continues to be a major global public health challenge, affecting 39.9 million people globally by the end of 2023. Sub-Saharan Africa bears a significant burden, contributing to 67% of cases. Malnutritio...

Statin-dependent and -independent pathways are associated with major adverse cardiovascular events in people with HIV.

The Journal of clinical investigation
BACKGROUNDStatin therapy lowers the risk of major adverse cardiovascular events (MACE) among people with HIV (PWH). Residual risk pathways contributing to excess MACE beyond LDL-cholesterol (LDL-C) are not well understood. Our objective was to evalua...

Lung and abdominal ultrasound accuracy for tuberculosis: An Indian prospective cohort study.

PloS one
BACKGROUND: Tuberculosis (TB) diagnosis remains a challenge, particularly in low-resource settings. Point-of-care ultrasound (POCUS) has shown promise, but most studies focus on HIV-infected populations. In the case of TB, data on lung ultrasound (LU...

Decoding HIV Discourse on Social Media: Large-Scale Analysis of 191,972 Tweets Using Machine Learning, Topic Modeling, and Temporal Analysis.

Journal of medical Internet research
BACKGROUND: HIV remains a global challenge, with stigma, financial constraints, and psychosocial barriers preventing people living with HIV from accessing health care services, driving them to seek information and support on social media. Despite the...