During the past 75 years, advances in cardiovascular science and technology have significantly reduced morbidity and mortality. In 2012, Drs Nabel and Braunwald reviewed this progress in , highlighting the landmark innovations that contributed to the...
BACKGROUND: Cells are the fundamental units of life, and understanding their diversity and functionality requires detailed characterization. The rise of single-cell omics data enables this, yet current deep learning approaches lack multi-scale interp...
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and current predictors such as lipoprotein (a) [Lp(a)] and risk scores have limitations. Automated machine learning (AutoML) offers the potential to improve CVD risk prediction ...
The Internet of Medical Things requires frameworks that ensure secure processing, computational efficiency, and scalability for continuous healthcare data streams. Existing solutions remain limited in their ability to support real-time anomaly detect...
Improving accuracy and timeliness for osteoporosis diagnosis could help prevent fragility fractures, morbidity, and mortality for older individuals. Osteoporosis is an often silent health condition, especially as regards vertebral fractures, and WHO ...
This study investigates the application of recent YOLO (You Only Look Once) algorithms for automated detection and classification of apical periodontitis using the Periapical Index (PAI) scoring system (1-5). A dataset of 699 digital periapical radio...
Infertility affects millions of couples worldwide, and in vitro fertilization is a key therapeutic strategy for achieving parenthood. Despite advances, the first IVF attempt fails in ~60% of patients, highlighting the need for innovative solutions to...
Africa's vast genetic diversity poses challenges for optimising drug treatments in the continent, which is exacerbated by the fact that drug discovery and development efforts have historically been performed outside Africa. This has led to suboptimal...
INTRODUCTION: Neuropsychiatric disorders encompass psychiatric and neurodegenerative diseases. These conditions are particularly challenging to diagnose in the elderly due to their overlapping cognitive, affective, and behavioural symptoms. Recent st...
BACKGROUND: Human-centered design (HCD) methodologies such as design thinking (DT), user-centered design, cocreation, and participatory design (PD) have been adopted to facilitate user and stakeholder involvement in the development of eHealth applica...
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