AIMC Topic: Humans

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Natural Language Processing to Identify Advance Care Planning Documentation in a Multisite Pragmatic Clinical Trial.

Journal of pain and symptom management
CONTEXT: Large multisite clinical trials studying decision-making when facing serious illness require an efficient method for abstraction of advance care planning (ACP) documentation from clinical text documents. However, the current gold standard me...

Active robotic technologies for total knee arthroplasty.

Archives of orthopaedic and trauma surgery
INTRODUCTION: When active robotic technologies for Total Knee Arthroplasty (TKA) were introduced over 20 years ago, broad usage of robotic technology was not felt to be needed as early data suggested no clear improvement in clinical outcomes compared...

Deep sr-DDL: Deep structurally regularized dynamic dictionary learning to integrate multimodal and dynamic functional connectomics data for multidimensional clinical characterizations.

NeuroImage
We propose a novel integrated framework that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract biomarkers of brain connectivity predictive of b...

Semi-supervised training of deep convolutional neural networks with heterogeneous data and few local annotations: An experiment on prostate histopathology image classification.

Medical image analysis
Convolutional neural networks (CNNs) are state-of-the-art computer vision techniques for various tasks, particularly for image classification. However, there are domains where the training of classification models that generalize on several datasets ...

Future minds and a new challenge to anti-natalism.

Bioethics
Some futurists and philosophers have urged that recent developments in biotechnology promise advancements that challenge standard accepted views of human nature, the self, and ethical obligation. Additionally, some have urged that developments in art...

Bayesian Modeling for the Detection of Adverse Events Underreporting in Clinical Trials.

Drug safety
INTRODUCTION: Safety underreporting is a recurrent issue in clinical trials that can impact patient safety and data integrity. Clinical quality assurance (QA) practices used to detect underreporting rely on on-site audits; however, adverse events (AE...