AIMC Topic: Hydrolysis

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Virtual Hydrolysis-Based Screening of Wheat-Derived DPP-IV Inhibitory Peptides: A Mechanistic Analysis Integrating Cell Experiments and Molecular Dynamics Simulations.

Journal of agricultural and food chemistry
Dipeptidyl peptidase-IV (DPP-IV) inhibitors play a critical role in the treatment of diabetes and metabolic diseases. This study combines computational simulations with experimental validation to identify peptides with potential DPP-IV inhibitory act...

Promoting lignocellulosic biorefinery by machine learning: progress, perspectives and challenges.

Bioresource technology
The lignocellulosic biorefinery involves pretreatment, enzymatic hydrolysis, mixed sugar fermentation, and optional anaerobic digestion. This pipeline could be effectively implemented through machine learning (ML)-guided process optimization and stra...

[Separation and screening of antioxidant peptides from based on nano flow liquid chromatography].

Se pu = Chinese journal of chromatography
As a rich source of high activity antioxidant peptides, is a key marine natural product with a high processing value. Due to the high complexity of fish tissues, high recovery extraction and high efficiency screening of the active antioxidant peptid...

Artificial neuronal networks (ANN) to model the hydrolysis of goat milk protein by subtilisin and trypsin.

The Journal of dairy research
The enzymatic hydrolysis of milk proteins yield final products with improved properties and reduced allergenicity. The degree of hydrolysis (DH) influences both technological (e.g., solubility, water binding capacity) and biological (e.g., angiotensi...

An Approach of Anomaly Detection and Neural Network Classifiers to Measure Cellulolytic Activity.

Combinatorial chemistry & high throughput screening
AIM AND OBJECTIVE: A common method used for massive detection of cellulolytic microorganisms is based on the formation of halos on solid medium. However, this is a subjective method and real-time monitoring is not possible. The objective of this work...

[Transformation of icariin by immobilized β-glucosidase and snailase].

Yao xue xue bao = Acta pharmaceutica Sinica
This study was performed to prepare immobilized β-glucosidase and snailase, then optimize and compare the process conditions for conversion of icariin. Immobilized β-glucosidase and snailase were prepared using crosslink-embedding method. The best co...

[Preparation of baicalein using thermophilic and sugar-tolerant beta-glucosidase].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
The reaction conditions of baicalin hydrolyzed into baicalein by a kind of thermophilic and sugar-tolerant beta-glucosidase were studied in this paper. The beta-glucosidase could catalyze baicalin into baicalein well in the acetic acid-sodium acetate...

[Biotransformation and safety of cotton stalk alkaline peroxide mechanical pulping waste liquor].

Wei sheng wu xue bao = Acta microbiologica Sinica
OBJECTIVE: We studied the conditions of culturing Bacillus subtilis SY1 to treat cotton stalk alkaline peroxide mechanical pulping waste water, and evaluated afterwards the safety of its release to plants and animals.