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Hyperparathyroidism, Primary

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Non-surgical management of primary hyperparathyroidism.

Best practice & research. Clinical endocrinology & metabolism
The purpose of this chapter is to discuss the options available for patients with primary hyperparathyrodism (PHPT) not undergoing parathyroidectomy (PTx). Adequate hydration should be recommended in all patients. Calcium intake should not be restric...

Parathyroid hormone in washout fluid seems to be superior to cytology for localization of the lesion in MIBI-negative patients with primary hyperparathyroidism.

Turkish journal of medical sciences
Background/aim: Primary hyperparathyroidism (PHPT) is characterized by increased calcium (Ca) and parathyroid hormone (PTH) levels. Surgical removal of the culprit hyperfunctioning parathyroid gland is the preferred treatment. In this study, we aimed...

Double hit! A unique case of resistant hypertension.

BMJ case reports
A middle-aged woman with obesity, hyperlipidaemia and diet-controlled diabetes was referred for resistant hypertension. Her blood pressure (BP) was uncontrolled on five medications, including a diuretic. Physical exam revealed a systolic ejection mur...

Development of an algorithm for intraoperative autofluorescence assessment of parathyroid glands in primary hyperparathyroidism using artificial intelligence.

Surgery
BACKGROUND: Previous work showed that normal and abnormal parathyroid glands exhibit different patterns of autofluorescence, with the former appearing brighter and more homogenous. However, an objective algorithm based on quantified measurements was ...

Deep learning-based detection of parathyroid adenoma by Tc-MIBI scintigraphy in patients with primary hyperparathyroidism.

Annals of nuclear medicine
OBJECTIVE: It is important to detect parathyroid adenomas by parathyroid scintigraphy with 99m-technetium sestamibi (Tc-MIBI) before surgery. This study aimed to develop and validate deep learning (DL)-based models to detect parathyroid adenoma in pa...

A visual deep learning model to predict abnormal versus normal parathyroid glands using intraoperative autofluorescence signals.

Journal of surgical oncology
BACKGROUND: Previous work demonstrated that abnormal versus normal parathyroid glands (PGs) exhibit different patterns of autofluorescence, with former appearing darker and more heterogenous. Our objective was to develop a visual artificial intellige...

Robot-Assisted Parathyroidectomy Using Indocyanine Green (ICG) Fluorescence in Primary Hyperparathyroidism.

Medicina (Kaunas, Lithuania)
: Surgical treatment for primary hyperparathyroidism (PHPT) has evolved from bilateral exploration through a long transcervical incision to focused parathyroidectomy with a minimal incision above the pathologic gland. Recently, endoscopic or robot-as...

Robotic parathyroidectomy is a feasible technique for primary hyperparathyroidism.

Langenbeck's archives of surgery
PURPOSE: Focused parathyroidectomy is the gold standard treatment modality for primary hyperparathyroidism, which allows accurate preoperative localization. Robotic parathyroidectomy has emerged as a feasible procedure for focused parathyroidectomy. ...