Alzheimer's disease (AD) is a neurodegenerative disorder that affects memory and cognitive functions. Manual diagnosis is prone to human error, often leading to misdiagnosis or delayed detection. MRI techniques help visualize the fine tissues of the ...
Visually impaired individuals suffer many problems in handling their everyday activities like road crossing, writing, finding an object, reading, and so on. However, many navigation methods are available, and efficient object detection (OD) methods f...
Using deep learning-based image restoration, we achieved high-resolution 4D imaging with minimal photodamage, revealing distinct localization and suggesting Lifeact-RFP-labeled actin microfilaments play a role in initiating cell plate formation. Phra...
Supracondylar humerus fractures in children are among the most common elbow fractures in pediatrics. However, their diagnosis can be particularly challenging due to the anatomical characteristics and imaging features of the pediatric skeleton. In rec...
SIGNIFICANCE: Automated segmentation of periarterial and perivenous capillary-free zones (CFZs) in optical coherence tomography angiography (OCTA) can significantly improve early detection and monitoring of diabetic retinopathy (DR), a leading cause ...
Subcellular diffusion in living systems reflects cellular processes and interactions. Recent advances in optical microscopy allow the tracking of this nanoscale diffusion of individual objects with unprecedented precision. However, the agnostic and a...
Computer methods and programs in biomedicine
May 7, 2025
BACKGROUND AND OBJECTIVE: Measuring the thickness of the glomerular basement membrane (GBM) and assessing the percentage of podocyte foot process effacement (%PFPE) are important for diagnosing non-neoplastic kidney diseases. However, when performed ...
The rapid evolution of deep learning has dramatically enhanced the field of medical image segmentation, leading to the development of models with unprecedented accuracy in analyzing complex medical images. Deep learning-based segmentation holds signi...
SIGNIFICANCE: Stroke is a leading cause of disability worldwide, necessitating rapid and accurate diagnosis to limit irreversible brain damage. However, many advanced imaging modalities (computerized tomography, magnetic resonance imaging) remain ina...
PURPOSE: Tumor-infiltrating lymphocytes (TILs) play a crucial role in host antitumor processes. High level of TILs is associated with better outcomes for patients. We aim to automatically quantify TILs without any nuclei annotation and further constr...
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