INTRODUCTION: The prepubertal stage is a critical period of body fat development, in which leptin and insulin re sistance has been associated, however, there are few studies in normal-weight prepubescents. Ob jective: To assess the relationship betwe...
Nocturnal hypoglycemia is a serious complication of insulin-treated diabetes, which commonly goes undetected. Continuous glucose monitoring (CGM) devices have enabled prediction of impending nocturnal hypoglycemia, however, prior efforts have been li...
Blood glycemic control is crucial for minimizing severe side effects in diabetes mellitus. Currently, two opposing treatment approaches exist: in formulaic methods, insulin care is calculated by parameter-based computation (i.e., correction factor, i...
Type 1 diabetes (T1D) is characterized by pancreatic beta cell dysfunction and insulin depletion. Over 40% of people with T1D manage their glucose through multiple injections of long-acting basal and short-acting bolus insulin, so-called multiple dai...
Type 1 diabetes (T1D) is a chronic health condition resulting from pancreatic beta cell dysfunction and insulin depletion. While automated insulin delivery systems are now available, many people choose to manage insulin delivery manually through insu...
Accurate estimations for the near future levels of blood glucose are crucial for Type 1 Diabetes Mellitus (T1DM) patients in order to be able to react on time and avoid hypo and hyper-glycemic episodes. Accurate predictions for blood glucose are the ...
Considering current insulin action profiles and the nature of glycemic responses to insulin, there is an acute need for longer term, accurate, blood glucose predictions to inform insulin dosing schedules and enable effective decision support for the...
Emerging data suggest that type 1 diabetes affects not only the β-cell-containing islets of Langerhans, but also the surrounding exocrine compartment. Using digital pathology, machine learning algorithms were applied to high-resolution, whole-slide i...
In the twenty-first century, the collaboration of control engineering and the healthcare sector has matured to some extent; however, the future will have promising opportunities, vast applications, and some challenges. Due to advancements in processi...
Biochemical and biophysical research communications
33706101
Free fatty acid receptor 1 (FFAR1 or GPR40) has attracted attention for the treatment of type 2 diabetes mellitus, and various small-molecule agonists have been developed. However, most FFAR1 agonists as well as endogenous ligands, such as linoleic a...