AIMC Topic: Knowledge Bases
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Collating the knowledge base for core outcome set development: developing and appraising the search strategy for a systematic review.
BMC medical research methodology
Mar 29, 2015
BACKGROUND: The COMET (Core Outcome Measures in Effectiveness Trials) Initiative is developing a publicly accessible online resource to collate the knowledge base for core outcome set development (COS) and the applied work from different health condi...
MorphoCol: An ontology-based knowledgebase for the characterisation of clinically significant bacterial colony morphologies.
Journal of biomedical informatics
Mar 25, 2015
BACKGROUND: One of the major concerns of the biomedical community is the increasing prevalence of antimicrobial resistant microorganisms. Recent findings show that the diversification of colony morphology may be indicative of the expression of virule...
Integrating biological knowledge based on functional annotations for biclustering of gene expression data.
Computer methods and programs in biomedicine
Mar 18, 2015
Gene expression data analysis is based on the assumption that co-expressed genes imply co-regulated genes. This assumption is being reformulated because the co-expression of a group of genes may be the result of an independent activation with respect...
Comparing a knowledge-driven approach to a supervised machine learning approach in large-scale extraction of drug-side effect relationships from free-text biomedical literature.
BMC bioinformatics
Mar 18, 2015
BACKGROUND: Systems approaches to studying drug-side-effect (drug-SE) associations are emerging as an active research area for both drug target discovery and drug repositioning. However, a comprehensive drug-SE association knowledge base does not exi...
HemOnc.org: A Collaborative Online Knowledge Platform for Oncology Professionals.
Journal of oncology practice
Mar 3, 2015
PURPOSE: Cancer care involves extensive knowledge about numerous chemotherapy drugs and chemotherapy regimens. This information is constantly evolving, and there has been no freely available, comprehensive, centralized repository of chemotherapy info...
Knowledge bases, clinical decision support systems, and rapid learning in oncology.
Journal of oncology practice
Feb 24, 2015
One of the most important benefits of health information technology is to assist the cognitive process of the human mind in the face of vast amounts of health data, limited time for decision making, and the complexity of the patient with cancer. Clin...
Evaluation of a knowledge-based planning solution for head and neck cancer.
International journal of radiation oncology, biology, physics
Jan 30, 2015
PURPOSE: Automated and knowledge-based planning techniques aim to reduce variations in plan quality. RapidPlan uses a library consisting of different patient plans to make a model that can predict achievable dose-volume histograms (DVHs) for new pati...
Diabetes knowledge in young adults: associations with hemoglobin A1C.
Families, systems & health : the journal of collaborative family healthcare
Jan 19, 2015
The purpose of this study was to quantify associations between hemoglobin A1C (A1C) and diabetes knowledge score using an assessment tool developed to evaluate the level of diabetes knowledge in young adults with Type 1 diabetes (T1DM) and their pare...
Landscape ethnoecological knowledge base and management of ecosystem services in a Székely-Hungarian pre-capitalistic village system (Transylvania, Romania).
Journal of ethnobiology and ethnomedicine
Jan 7, 2015
BACKGROUND: Previous studies showed an in-depth ecological understanding by traditional people of managing natural resources. We studied the landscape ethnoecological knowledge (LEEK) of Székelys on the basis of 16-19(th) century village laws. We ana...
Enabling the curation of your pharmacogenetic study.
Clinical pharmacology and therapeutics
Dec 20, 2014
As pharmacogenomics becomes integrated into clinical practice, curation of published studies becomes increasingly important. At the Pharmacogenomics Knowledgebase (PharmGKB; www.pharmgkb.org), pharmacogenetic associations reported in published articl...
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