AIMC Topic: Knowledge Bases
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Using drug knowledgebase information to distinguish between look-alike-sound-alike drugs.
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2018
OBJECTIVE: To extract drug indications from a commercial drug knowledgebase and determine to what extent drug indications can discriminate between look-alike-sound-alike (LASA) drugs.
UMLS to DBPedia link discovery through circular resolution.
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2018
OBJECTIVE: The goal of this work is to map Unified Medical Language System (UMLS) concepts to DBpedia resources using widely accepted ontology relations from the Simple Knowledge Organization System (skos:exactMatch, skos:closeMatch) and from the Res...
Toward a normalized clinical drug knowledge base in China-applying the RxNorm model to Chinese clinical drugs.
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2018
OBJECTIVE: In recent years, electronic health record systems have been widely implemented in China, making clinical data available electronically. However, little effort has been devoted to making drug information exchangeable among these systems. Th...
Characteristics of knowledge content in a curated online evidence library.
Journal of the American Medical Informatics Association : JAMIA
May 1, 2018
OBJECTIVE: To describe types of recommendations represented in a curated online evidence library, report on the quality of evidence-based recommendations pertaining to diagnostic imaging exams, and assess underlying knowledge representation.
Reactome diagram viewer: data structures and strategies to boost performance.
Bioinformatics (Oxford, England)
Apr 1, 2018
MOTIVATION: Reactome is a free, open-source, open-data, curated and peer-reviewed knowledgebase of biomolecular pathways. For web-based pathway visualization, Reactome uses a custom pathway diagram viewer that has been evolved over the past years. He...
Testing the actual equivalence of automatically generated items.
Behavior research methods
Feb 1, 2018
If the automatic item generation is used for generating test items, the question of how the equivalence among different instances may be tested is fundamental to assure an accurate assessment. In the present research, the question was dealt by using ...
BioMuta and BioXpress: mutation and expression knowledgebases for cancer biomarker discovery.
Nucleic acids research
Jan 4, 2018
Single-nucleotide variation and gene expression of disease samples represent important resources for biomarker discovery. Many databases have been built to host and make available such data to the community, but these databases are frequently limited...
Gramene 2018: unifying comparative genomics and pathway resources for plant research.
Nucleic acids research
Jan 4, 2018
Gramene (http://www.gramene.org) is a knowledgebase for comparative functional analysis in major crops and model plant species. The current release, #54, includes over 1.7 million genes from 44 reference genomes, most of which were organized into 62,...
The Reactome Pathway Knowledgebase.
Nucleic acids research
Jan 4, 2018
The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations-an extended version of a clas...
iPTMnet: an integrated resource for protein post-translational modification network discovery.
Nucleic acids research
Jan 4, 2018
Protein post-translational modifications (PTMs) play a pivotal role in numerous biological processes by modulating regulation of protein function. We have developed iPTMnet (http://proteininformationresource.org/iPTMnet) for PTM knowledge discovery, ...
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