Capillary microfluidic chips (CMCs) enable passive liquid transport via surface tension and wettability gradients, making them central to point-of-care diagnostics and biomedical sensing. However, accurate analysis of capillary-driven flow experiment...
BACKGROUND: Head and neck cancer (HNC) presents significant research challenges due to the complexity of its tumor microenvironment (TME) and the heterogeneity across different cancer subtypes. Recent advancements in three-dimensional (3D) culture mo...
The frequent global outbreaks of viral infectious diseases have significantly heightened the urgent demand for molecular testing at home. However, the labor-intensive sample preparation and nucleic acid amplification steps, along with the complexity ...
International journal of pharmaceutics
Jul 5, 2025
Lab-on-a-chip (LoC) technologies have emerged as transformative tools in cancer research, particularly in evaluating drug resistance, which remains a significant barrier to effective treatment. These miniaturized platforms allow for the integration o...
(Fluoro)quinolones (FQs) pose significant threats to public health due to their widespread use and persistence in food and water sources. Given the extensive variety of FQs, testing each compound individually is prohibitively expensive and time-consu...
Industrial fungi are pivotal candidates for the production of a diverse array of bioproducts. To enhance their productivity, these strains are frequently subjected to genetic modifications. Following transformation, the selection of optimal productio...
Microfluidic biosensors offer a promising solution for real-time analysis of coronaviruses with minimal sample volumes. This study optimizes a biochip for the rapid detection of SARS-CoV-2 using the Taguchi orthogonal table L(3), which comprises nine...
Artificial intelligence (AI) is reshaping preclinical drug research offering innovative alternatives to traditional animal testing. Advanced techniques, including machine learning (ML), deep learning (DL), AI-powered digital twins (DTs), and AI-enhan...
Point-of-care testing (POCT) with multiplexed capability, ultrahigh sensitivity, affordable smart devices, and user-friendly operation is critically needed for clinical diagnostics and food safety. This study presents a deep-learning-assisted microfl...
Lung cancer exhibits strong heterogeneity, and its early diagnosis and precise subtyping are of great importance, as they can increase the ability to deliver personalized medicines by tailoring therapy regimens. Tissue biopsy, albeit the gold standar...
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