AIMC Topic: Lung Neoplasms

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Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study.

BMC cancer
BACKGROUND: Identifying high risk factors and predicting lung cancer incidence risk are essential to prevention and intervention of lung cancer for the elderly. We aim to develop lung cancer incidence risk prediction model in the elderly to facilitat...

Deep-learning based electromagnetic navigation system for transthoracic percutaneous puncture of small pulmonary nodules.

Scientific reports
Percutaneous transthoracic puncture of small pulmonary nodules is technically challenging. We developed a novel electromagnetic navigation puncture system for the puncture of sub-centimeter lung nodules by combining multiple deep learning models with...

Using natural language processing to identify emergency department patients with incidental lung nodules requiring follow-up.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
OBJECTIVES: For emergency department (ED) patients, lung cancer may be detected early through incidental lung nodules (ILNs) discovered on chest CTs. However, there are significant errors in the communication and follow-up of incidental findings on E...

Development of a clinical prediction model for benign and malignant pulmonary nodules with a CTR ≥ 50% utilizing artificial intelligence-driven radiomics analysis.

BMC medical imaging
OBJECTIVE: In clinical practice, diagnosing the benignity and malignancy of solid-component-predominant pulmonary nodules is challenging, especially when 3D consolidation-to-tumor ratio (CTR) ≥ 50%, as malignant ones are more invasive. This study aim...

Classification of NSCLC subtypes using lung microbiome from resected tissue based on machine learning methods.

NPJ systems biology and applications
Classification of adenocarcinoma (AC) and squamous cell carcinoma (SCC) poses significant challenges for cytopathologists, often necessitating clinical tests and biopsies that delay treatment initiation. To address this, we developed a machine learni...

Automatic machine learning accurately predicts the efficacy of immunotherapy for patients with inoperable advanced non-small cell lung cancer using a computed tomography-based radiomics model.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: Patients with advanced non-small cell lung cancer (NSCLC) have varying responses to immunotherapy, but there are no reliable, accepted biomarkers to accurately predict its therapeutic efficacy. The present study aimed to construct individual...

Generative Adversarial Networks With Radiomics Supervision for Lung Lesion Generation.

IEEE transactions on bio-medical engineering
Data-driven methods for lesion generation are quickly emerging due to the need for realistic imaging targets for image quality assessment and virtual clinical trials. We proposed a generative adversarial network (GAN) architecture for conditional gen...

MCF-DTI: Multi-Scale Convolutional Local-Global Feature Fusion for Drug-Target Interaction Prediction.

Molecules (Basel, Switzerland)
Predicting drug-target interactions (DTIs) is a crucial step in the development of new drugs and drug repurposing. In this paper, we propose a novel drug-target prediction model called MCF-DTI. The model utilizes the SMILES representation of drugs an...

A benchmark of deep learning approaches to predict lung cancer risk using national lung screening trial cohort.

Scientific reports
Deep learning (DL) methods have demonstrated remarkable effectiveness in assisting with lung cancer risk prediction tasks using computed tomography (CT) scans. However, the lack of comprehensive comparison and validation of state-of-the-art (SOTA) mo...