Computer methods and programs in biomedicine
Mar 27, 2025
BACKGROUND AND OBJECTIVE: In the medical field of digital pathology, many tasks rely on visual assessments of tissue patterns or cells, presenting an opportunity to apply computer vision methods. However, acquiring a substantial number of annotations...
AIMS: In routine diagnosis of lymphoma, initial non-specialist triage is carried out when the sample is biopsied to determine if referral to specialised haematopathology services is needed. This places a heavy burden on pathology services, causes del...
Mature B-cell neoplasms (MBNs) are clonal proliferative diseases encompassing over 40 subtypes. The WHO classification (morphology, immunology, cytogenetics and molecular biology) provides comprehensive diagnostic understandings. However, MBN subtypi...
Histological assessment of centroblasts is an important evaluation in the diagnosis of follicular lymphoma, but there is substantial observer variation in assessment among hematopathologists. We aimed to perform quantitative morphological analysis of...
Laboratory investigation; a journal of technical methods and pathology
May 29, 2020
A pathological evaluation is one of the most important methods for the diagnosis of malignant lymphoma. A standardized diagnosis is occasionally difficult to achieve even by experienced hematopathologists. Therefore, established procedures including ...
Archives of pathology & laboratory medicine
Jan 2, 2022
CONTEXT.—: Large cell transformation (LCT) of indolent B-cell lymphomas, such as follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL), signals a worse prognosis, at which point aggressive chemotherapy is initiated. Although LCT is relative...
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