Human proteins are crucial players in both health and disease. Understanding their molecular landscape is a central topic in biological research. Here, we present an extensive dataset of predicted protein structures for 42,042 distinct human proteins...
Diabetic retinopathy (DR) is one of the leading causes of adult blindness in the United States. Although studies applying traditional statistical methods have revealed that heavy metals may be essential environmental risk factors for diabetic retinop...
Humans produce two forms of cognitively complex vocalizations: speech and song. It is debated whether these differ based primarily on culturally specific, learned features, or if acoustical features can reliably distinguish them. We study the spectro...
Freezing of gait (FOG) is a debilitating problem that markedly impairs the mobility and independence of 38-65% of people with Parkinson's disease. During a FOG episode, patients report that their feet are suddenly and inexplicably "glued" to the floo...
Physical chemistry chemical physics : PCCP
Jun 6, 2024
Myeloid cell leukemia 1 (Mcl1), a critical protein that regulates apoptosis, has been considered as a promising target for antitumor drugs. The conventional pharmacophore screening approach has limitations in conformation sampling and data mining. He...
IEEE journal of biomedical and health informatics
Jun 6, 2024
In this study, we present a novel approach for predicting interventions for patients in the intensive care unit using a multivariate time series graph convolutional neural network. Our method addresses two critical challenges: the need for timely and...
IEEE journal of biomedical and health informatics
Jun 6, 2024
Federated learning (FL) enables collaborative training of machine learning models across distributed medical data sources without compromising privacy. However, applying FL to medical image analysis presents challenges like high communication overhea...
IEEE journal of biomedical and health informatics
Jun 6, 2024
Machine learning (ML) has revolutionized medical image-based diagnostics. In this review, we cover a rapidly emerging field that can be potentially significantly impacted by ML - eye tracking in medical imaging. The review investigates the clinical, ...
IEEE journal of biomedical and health informatics
Jun 6, 2024
The concept of Federated Learning (FL) is a distributed-based machine learning (ML) approach that trains its model using edge devices. Its focus is on maintaining privacy by transmitting gradient updates along with users' learning parameters to the g...
OBJECTIVES: Opioid nonadherence represents a significant barrier to cancer pain treatment efficacy. However, there is currently no effective prediction method for opioid adherence in patients with cancer pain. We aimed to develop and validate a machi...
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