AIMC Topic: Machine Learning

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Inferring neural activity before plasticity as a foundation for learning beyond backpropagation.

Nature neuroscience
For both humans and machines, the essence of learning is to pinpoint which components in its information processing pipeline are responsible for an error in its output, a challenge that is known as 'credit assignment'. It has long been assumed that c...

Active Learning Approach for Guiding Site-of-Metabolism Measurement and Annotation.

Journal of chemical information and modeling
The ability to determine and predict metabolically labile atom positions in a molecule (also called "sites of metabolism" or "SoMs") is of high interest to the design and optimization of bioactive compounds, such as drugs, agrochemicals, and cosmetic...

Deep learning-based prediction of in-hospital mortality for sepsis.

Scientific reports
As a serious blood infection disease, sepsis is characterized by a high mortality risk and many complications. Accurate assessment of mortality risk of patients with sepsis can help physicians in Intensive Care Unit make optimal clinical decisions, w...

Discovery of sparse, reliable omic biomarkers with Stabl.

Nature biotechnology
Adoption of high-content omic technologies in clinical studies, coupled with computational methods, has yielded an abundance of candidate biomarkers. However, translating such findings into bona fide clinical biomarkers remains challenging. To facili...

An Evaluation of the Efficacy of Machine Learning in Predicting Thyrotoxicosis and Hypothyroidism: A Comparative Assessment of Biochemical Test Parameters Used in Different Health Checkups.

Internal medicine (Tokyo, Japan)
Objective This study assessed the efficacy of machine learning in predicting thyrotoxicosis and hypothyroidism [thyroid-stimulating hormone >10.0 mIU/L] by leveraging age and sex as variables and integrating biochemical test parameters used by the Ja...

Cystic renal mass screening: machine-learning-based radiomics on unenhanced computed tomography.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: The present study compares the diagnostic performance of unenhanced computed tomography (CT) radiomics-based machine learning (ML) classifiers and a radiologist in cystic renal masses (CRMs).

Enhancing safety of construction workers in Korea: an integrated text mining and machine learning framework for predicting accident types.

International journal of injury control and safety promotion
Construction workers face a high risk of various occupational accidents, many of which can result in fatalities. This study aims to develop a prediction model for nine prevalent types of construction accidents, utilizing construction tasks, activitie...

Detection of Chylous Plasma Based on Machine Learning and Hyperspectral Techniques.

Applied spectroscopy
Chylous blood is the main cause of unqualified and scrapped blood among volunteer blood donors. Therefore, a diagnostic method that can quickly and accurately identify chylous blood before donation is needed. In this study, the GaiaSorter "Gaia" hype...

Antimalarial Drug Combination Predictions Using the Machine Learning Synergy Predictor (MLSyPred©) tool.

Acta parasitologica
PURPOSE: Antimalarial drug resistance is a global public health problem that leads to treatment failure. Synergistic drug combinations can improve treatment outcomes and delay the development of drug resistance. Here, we describe the implementation o...

MAPS: pathologist-level cell type annotation from tissue images through machine learning.

Nature communications
Highly multiplexed protein imaging is emerging as a potent technique for analyzing protein distribution within cells and tissues in their native context. However, existing cell annotation methods utilizing high-plex spatial proteomics data are resour...