AIMC Topic: Machine Learning

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Critical assessment of AI in drug discovery.

Expert opinion on drug discovery
: Artificial Intelligence (AI) has become a component of our everyday lives, with applications ranging from recommendations on what to buy to the analysis of radiology images. Many of the techniques originally developed for other fields such as langu...

Iterative single-cell multi-omic integration using online learning.

Nature biotechnology
Integrating large single-cell gene expression, chromatin accessibility and DNA methylation datasets requires general and scalable computational approaches. Here we describe online integrative non-negative matrix factorization (iNMF), an algorithm for...

A Machine Vision Approach for Bioreactor Foam Sensing.

SLAS technology
Machine vision is a powerful technology that has become increasingly popular and accurate during the last decade due to rapid advances in the field of machine learning. The majority of machine vision applications are currently found in consumer elect...

Sex-Specific Classification of Drug-Induced Torsade de Pointes Susceptibility Using Cardiac Simulations and Machine Learning.

Clinical pharmacology and therapeutics
Torsade de Pointes (TdP), a rare but lethal ventricular arrhythmia, is a toxic side effect of many drugs. To assess TdP risk, safety regulatory guidelines require quantification of hERG channel block in vitro and QT interval prolongation in vivo for ...

A Machine Learning Approach to First Pass Reperfusion in Mechanical Thrombectomy: Prediction and Feature Analysis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
INTRODUCTION: Novel machine learning (ML) methods are being investigated across medicine for their predictive capabilities while boasting increased adaptability and generalizability. In our study, we compare logistic regression with machine learning ...

Exploring photoacoustic spectroscopy-based machine learning together with metabolomics to assess breast tumor progression in a xenograft model ex vivo.

Laboratory investigation; a journal of technical methods and pathology
In the current study, a breast tumor xenograft was established in athymic nude mice by subcutaneous injection of the MCF-7 cell line and assessed the tumor progression by photoacoustic spectroscopy combined with machine learning tools. The advancemen...

Radiomics analysis on CT images for prediction of radiation-induced kidney damage by machine learning models.

Computers in biology and medicine
INTRODUCTION: We aimed to assess the power of radiomic features based on computed tomography to predict risk of chronic kidney disease in patients undergoing radiation therapy of abdominal cancers.

Artificial Intelligence-based methods in head and neck cancer diagnosis: an overview.

British journal of cancer
BACKGROUND: This paper reviews recent literature employing Artificial Intelligence/Machine Learning (AI/ML) methods for diagnostic evaluation of head and neck cancers (HNC) using automated image analysis.

Dielectric Polymer Property Prediction Using Recurrent Neural Networks with Optimizations.

Journal of chemical information and modeling
Despite the growing success of machine learning for predicting structure-property relationships in molecules and materials, such as predicting the dielectric properties of polymers, it is still in its infancy. We report on the effectiveness of solvin...

Machine learning analysis to predict the need for ankle foot orthosis in patients with stroke.

Scientific reports
We investigated the potential of machine learning techniques, at an early stage after stroke, to predict the need for ankle-foot orthosis (AFO) in stroke patients. We retrospectively recruited 474 consecutive stroke patients. The need for AFO during ...