AIMC Topic: Machine Learning

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Enhancing cryo-EM structure prediction with DeepTracer and AlphaFold2 integration.

Briefings in bioinformatics
Understanding the protein structures is invaluable in various biomedical applications, such as vaccine development. Protein structure model building from experimental electron density maps is a time-consuming and labor-intensive task. To address the ...

Panoramic imaging errors in machine learning model development: a systematic review.

Dento maxillo facial radiology
OBJECTIVES: To investigate the management of imaging errors from panoramic radiography (PAN) datasets used in the development of machine learning (ML) models.

Prediction of DNA i-motifs via machine learning.

Nucleic acids research
i-Motifs (iMs), are secondary structures formed in cytosine-rich DNA sequences and are involved in multiple functions in the genome. Although putative iM forming sequences are widely distributed in the human genome, the folding status and strength of...

[Screening for Characteristic Genes of Different Traditional Chinese Medicine Syndromes of Psoriasis Vulgaris: A Study Based on Bioinformatics and Machine Learning].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVE: To screen for the key characteristic genes of the psoriasis vulgaris (PV) patients with different Traditional Chinese Medicine (TCM) syndromes, including blood-heat syndrome (BHS), blood stasis syndrome (BSS), and blood-dryness syndrome (B...

Incorporating temporal information during feature engineering bolsters emulation of spatio-temporal emergence.

Bioinformatics (Oxford, England)
MOTIVATION: Emergent biological dynamics derive from the evolution of lower-level spatial and temporal processes. A long-standing challenge for scientists and engineers is identifying simple low-level rules that give rise to complex higher-level dyna...

CryoTransformer: a transformer model for picking protein particles from cryo-EM micrographs.

Bioinformatics (Oxford, England)
MOTIVATION: Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structures of large protein complexes. Picking single protein particles from cryo-EM micrographs (images) is a crucial step in reconstructing protein structure...