BACKGROUND: When left untreated, age-related macular degeneration (AMD) is the leading cause of vision loss in people over fifty in the US. Currently it is estimated that about eight million US individuals have the intermediate stage of AMD that is o...
Age-related Macular Degeneration (AMD) affects the central vision of aged people. It can be diagnosed due to the presence of drusen, Geographic Atrophy (GA) and Choroidal Neovascularization (CNV) in the fundus images. It is labor intensive and time-c...
Age-related Macular Degeneration (AMD) is an irreversible and chronic medical condition characterized by drusen, Choroidal Neovascularization (CNV) and Geographic Atrophy (GA). AMD is one of the major causes of visual loss among elderly people. It is...
BACKGROUND: To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD).
OBJECTIVES: To compare the effectiveness of expert-designed machine learning models and code-free automated machine learning (AutoML) models in classifying optical coherence tomography (OCT) images for detecting age-related macular degeneration (AMD)...
Photodiagnosis and photodynamic therapy
Jun 1, 2025
PURPOSE: This study aimed to establish and validate a prediction model based on machine learning methods and SHAP algorithm to predict response to anti-vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration ...
Studies in health technology and informatics
May 15, 2025
Optical Coherence Tomography (OCT) has become an indispensable imaging modality in ophthalmology, providing high-resolution cross-sectional images of the retina. Accurate classification of OCT images is crucial for diagnosing retinal diseases such as...
Deep learning models hold significant promise for disease diagnosis but often lack transparency in their decision-making processes, limiting trust and hindering clinical adoption. This study introduces a novel multi-task learning framework to enhance...
Translational vision science & technology
Feb 3, 2025
PURPOSE: To evaluate the performance of various approaches of processing three-dimensional (3D) optical coherence tomography (OCT) images for deep learning models in predicting area and future growth rate of geographic atrophy (GA) lesions caused by ...
Age-related macular degeneration (AMD) is a progressive degenerative retinal disease and a leading cause of blindness in older adults worldwide. According to numerous studies, the number of affected individuals reached 196 million in 2020, with proje...
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