AIMC Topic: Macular Degeneration

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Comparing humans and deep learning performance for grading AMD: A study in using universal deep features and transfer learning for automated AMD analysis.

Computers in biology and medicine
BACKGROUND: When left untreated, age-related macular degeneration (AMD) is the leading cause of vision loss in people over fifty in the US. Currently it is estimated that about eight million US individuals have the intermediate stage of AMD that is o...

Novel risk index for the identification of age-related macular degeneration using radon transform and DWT features.

Computers in biology and medicine
Age-related Macular Degeneration (AMD) affects the central vision of aged people. It can be diagnosed due to the presence of drusen, Geographic Atrophy (GA) and Choroidal Neovascularization (CNV) in the fundus images. It is labor intensive and time-c...

Local configuration pattern features for age-related macular degeneration characterization and classification.

Computers in biology and medicine
Age-related Macular Degeneration (AMD) is an irreversible and chronic medical condition characterized by drusen, Choroidal Neovascularization (CNV) and Geographic Atrophy (GA). AMD is one of the major causes of visual loss among elderly people. It is...

Comparative Analysis of Automated vs. Expert-Designed Machine Learning Models in Age-Related Macular Degeneration Detection and Classification.

Turkish journal of ophthalmology
OBJECTIVES: To compare the effectiveness of expert-designed machine learning models and code-free automated machine learning (AutoML) models in classifying optical coherence tomography (OCT) images for detecting age-related macular degeneration (AMD)...

Predicting response to anti-VEGF therapy in neovascular age-related macular degeneration using random forest and SHAP algorithms.

Photodiagnosis and photodynamic therapy
PURPOSE: This study aimed to establish and validate a prediction model based on machine learning methods and SHAP algorithm to predict response to anti-vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration ...

Leveraging Vision Transformers in Multimodal Models for Retinal OCT Analysis.

Studies in health technology and informatics
Optical Coherence Tomography (OCT) has become an indispensable imaging modality in ophthalmology, providing high-resolution cross-sectional images of the retina. Accurate classification of OCT images is crucial for diagnosing retinal diseases such as...

Enhancing medical explainability in deep learning for age-related macular degeneration diagnosis.

Scientific reports
Deep learning models hold significant promise for disease diagnosis but often lack transparency in their decision-making processes, limiting trust and hindering clinical adoption. This study introduces a novel multi-task learning framework to enhance...

Deep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging.

Translational vision science & technology
PURPOSE: To evaluate the performance of various approaches of processing three-dimensional (3D) optical coherence tomography (OCT) images for deep learning models in predicting area and future growth rate of geographic atrophy (GA) lesions caused by ...

[Artificial intelligence in assessment of individual risks of age-related macular degeneration progression].

Vestnik oftalmologii
Age-related macular degeneration (AMD) is a progressive degenerative retinal disease and a leading cause of blindness in older adults worldwide. According to numerous studies, the number of affected individuals reached 196 million in 2020, with proje...