BACKGROUND: Age-related macular degeneration (AMD) is a major cause of irreversible visual impairment, with dry AMD being the most prevalent form. Programmed cell death of retinal pigment epithelium (RPE) cells is a central mechanism in the pathogene...
PURPOSE: The purpose of this study was to develop a deep learning algorithm for detecting and quantifying incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) and complete retinal pigment epithelium and outer retinal atrophy (cRORA...
PURPOSE: To develop a novel classification of highly myopic eyes using artificial intelligence (AI) and investigate its relationship with contrast sensitivity function (CSF) and fundus features.
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Jul 11, 2024
Artificial intelligence (AI) has demonstrated revolutionary potential and wide-ranging applications in the comprehensive management of fundus diseases, yet it faces challenges in clinical translation, data quality, algorithm interpretability, and cro...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Retinal lesion is a cause of age-related macular degeneration that poses a big threat to elderly population. The accurate detection and segmentation of retinal lesions benefits the early diagnosis of age-related macular degeneration and monitoring of...
PURPOSE: AI algorithms have shown impressive performance in segmenting geographic atrophy (GA) from fundus autofluorescence (FAF) images. However, selection of artificial intelligence (AI) architecture is an important variable in model development. H...
Investigative ophthalmology & visual science
Jun 3, 2024
PURPOSE: The purpose of this study was to develop and validate prediction model for myopic macular degeneration (MMD) progression in patients with high myopia.
Translational vision science & technology
Jun 3, 2024
PURPOSE: The subsidence of the outer plexiform layer (OPL) is an important imaging biomarker on optical coherence tomography (OCT) associated with early outer retinal atrophy and a risk factor for progression to geographic atrophy in patients with in...
Geographic atrophy (GA) secondary to age-related macular degeneration is among the most common causes of irreversible vision loss in industrialized countries. Recently, two therapies have been approved by the US FDA. However, given the nature of thei...