Bioorganic & medicinal chemistry letters
Jun 16, 2016
The present study describes the synthesis of two new series of 3-hydroxy-N-(4-oxo-2-phenyl-1,3-thiazinan-3-yl)-8-(trifluoromethyl)quinoline-2-carboxamide derivatives (4a-j) and 3-((7-chloroquinolin-4-ylamino)methyl)-2-phenyl-1,3-thiazinan-4-one deriv...
CONTEXT: With the advent of new imaging modalities, radiologists are faced with handling increasing volumes of data for diagnosis and treatment planning. The use of automated and intelligent systems is becoming essential in such a scenario. Machine l...
Covering: 2000. 01 to 2025. 03The soaring demand for novel drugs has led to an increase in the requirement for smart methods to aid in the exploration of microbial natural products (NPs). Cutting-edge metabolomics excels at prompt identification of c...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Sep 5, 2025
Traditionally, wine quality and certification have been assessed through sensory analysis by trained tasters. However, this method has the limitation of relying on highly specialized individuals who are typically trained to evaluate only specific typ...
Multimodality imaging is an emerging research topic in neuro-oncology for its potential of being able to demonstrate tumours in a more comprehensive manner. Diffusion-weighted magnetic resonance imaging (dMRI) and proton magnetic resonance spectrosco...
Journal of agricultural and food chemistry
Jul 30, 2025
Besides food authentication control based on acknowledged analytical methods, nowadays there is a continuous attempt to develop new approaches for unambiguously differentiating distinct food commodities. In this regard, current tendencies involve Art...
Advancements in structural biology have significantly deepened our understanding of plant proteins, which are central to critical biological functions such as photosynthesis, metabolism, signal transduction, and structural architechture. Gaining insi...
Chembiochem : a European journal of chemical biology
Jun 3, 2025
H nuclear magnetic resonance (NMR) spectroscopy plays an important role in the pharmaceutical industry, but for complex substances, spectral analysis is challenging due to the narrow chemical shift range and signal splitting caused by scalar coupling...
Accurate quantification of metabolites in magnetic resonance spectroscopy (MRS) is challenged by low signal-to-noise ratio (SNR), overlapping metabolites, and various artifacts. Particularly, unknown and unparameterized baseline effects obscure the q...
Purpose To develop and evaluate the performance of NNFit, a self-supervised deep learning method for quantification of high-resolution short-echo-time (TE) echo-planar spectroscopic imaging (EPSI) datasets, with the goal of addressing the computation...
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