Malaria is an infectious disease that affects over 216 million people worldwide, killing over 445,000 patients annually. Due to the constant emergence of parasitic resistance to the current antimalarial drugs, the discovery of new drug candidates is ...
Frontiers in bioscience (Landmark edition)
Jan 1, 2020
Malaria is an infectious disease caused by parasitic protozoans of the Plasmodium family. These parasites are transmitted by mosquitos which are common in certain parts of the world. Based on their specific climates, these regions have been classifie...
BACKGROUND AND OBJECTIVE: Most previous studies adopted single traditional time series models to predict incidences of malaria. A single model cannot effectively capture all the properties of the data structure. However, a stacking architecture can s...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Dec 25, 2019
The Malaria burden was an escalating global encumbrance and need to be addressed with critical care. Anti-malarial drug discovery was integrated with supervised machine learning (ML) models to identify potent thiazolyl-traizine derivatives. This assi...
BACKGROUND: Near infrared spectroscopy (NIRS) is currently complementing techniques to age-grade mosquitoes. NIRS classifies lab-reared and semi-field raised mosquitoes into < or ≥ 7 days old with an average accuracy of 80%, achieved by training a re...
BACKGROUND: The propensity of different Anopheles mosquitoes to bite humans instead of other vertebrates influences their capacity to transmit pathogens to humans. Unfortunately, determining proportions of mosquitoes that have fed on humans, i.e. Hum...
BACKGROUND: Since the beginning of the 21st century, the amount of data obtained from public health surveillance has increased dramatically due to the advancement of information and communications technology and the data collection systems now in pla...
The parasite Plasmodium falciparum is the main cause of severe malaria (SM). Despite treatment with antimalarial drugs, more than 400,000 deaths are reported every year, mainly in African children. The diversity of clinical presentations associated w...
Accurate and immediate diagnosis of malaria is important for medication of the infectious disease. Conventional methods for diagnosing malaria are time consuming and rely on the skill of experts. Therefore, an automatic and simple diagnostic modality...
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