AIMC Topic: Materials Testing

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Quantification of loading in biomechanical testing: the influence of dissection sequence.

Journal of biomechanics
Sequential dissection is a technique used to investigate loads experienced by articular tissues. When the joint of interest is tested in an unconstrained manner, its kinematics change with each tissue removal. To address this limitation, sufficiently...

Corrugated paraffin nanocomposite films as large stroke thermal actuators and self-activating thermal interfaces.

ACS applied materials & interfaces
High performance active materials are of rapidly growing interest for applications including soft robotics, microfluidic systems, and morphing composites. In particular, paraffin wax has been used to actuate miniature pumps, solenoid valves, and comp...

Multicomponent signal unmixing from nanoheterostructures: overcoming the traditional challenges of nanoscale X-ray analysis via machine learning.

Nano letters
The chemical composition of core-shell nanoparticle clusters have been determined through principal component analysis (PCA) and independent component analysis (ICA) of an energy-dispersive X-ray (EDX) spectrum image (SI) acquired in a scanning trans...

Mechanical characterization of bone anchors used with a bone-attached, parallel robot for skull surgery.

Medical engineering & physics
Bone-attached robots and microstereotactic frames, intended for deep brain stimulation and minimally invasive cochlear implantation, typically attach to a patient's skull via bone anchors. A rigid and reliable link between such devices and the skull ...

A machine learning model exploring creep performance of dental composites.

Dental materials : official publication of the Academy of Dental Materials
OBJECTIVES: Viscoelastic creep behaviour of RBCs determines their dimensional stability and thus contributes to their clinical performance. However, due to complex material compositional variations and differing testing protocols, comparing and analy...

A Modular, Mechanical Knee Model for the Development and Validation of Robotic Testing Methodologies.

Journal of biomechanical engineering
Six-degree-of-freedom robotic testing is used to gain insight into knee function by measuring the biomechanics of cadaveric knees. However, it can be challenging to use cadaveric knees to validate robotic testing methodologies and to compare methodol...

Identification and Classification of Functional Split G-Quadruplexes Using Machine Learning-Guided Activity Screening.

ACS applied bio materials
Split G-quadruplexes are considered excellent tools for biosensing and diagnostics, but splitting G-quadruplexes may often lead to a loss of function, limiting their effectiveness. This study aims to identify and classify functional split G-quadruple...

Comparative analysis of deep learning models for predicting biocompatibility in tissue scaffold images.

Computers in biology and medicine
MOTIVATION: Bioprinting enables the creation of complex tissue scaffolds, which are vital for tissue engineering. However, predicting scaffold biocompatibility before fabrication remains a critical challenge, potentially leading to inefficiencies and...

Machine-Learning Framework to Predict the Performance of Lipid Nanoparticles for Nucleic Acid Delivery.

ACS applied bio materials
Lipid nanoparticles (LNPs) are highly effective carriers for gene therapies, including mRNA and siRNA delivery, due to their ability to transport nucleic acids across biological membranes, low cytotoxicity, improved pharmacokinetics, and scalability....