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Medical Informatics

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Discovering hidden knowledge through auditing clinical diagnostic knowledge bases.

Journal of biomedical informatics
OBJECTIVE: Evaluate potential for data mining auditing techniques to identify hidden concepts in diagnostic knowledge bases (KB). Improving completeness enhances KB applications such as differential diagnosis and patient case simulation.

Prediction task guided representation learning of medical codes in EHR.

Journal of biomedical informatics
There have been rapidly growing applications using machine learning models for predictive analytics in Electronic Health Records (EHR) to improve the quality of hospital services and the efficiency of healthcare resource utilization. A fundamental an...

A study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set.

Journal of biomedical informatics
Recently, recurrent neural networks (RNNs) have been applied in predicting disease onset risks with Electronic Health Record (EHR) data. While these models demonstrated promising results on relatively small data sets, the generalizability and transfe...

From lexical regularities to axiomatic patterns for the quality assurance of biomedical terminologies and ontologies.

Journal of biomedical informatics
Ontologies and terminologies have been identified as key resources for the achievement of semantic interoperability in biomedical domains. The development of ontologies is performed as a joint work by domain experts and knowledge engineers. The maint...

Medical concept normalization in social media posts with recurrent neural networks.

Journal of biomedical informatics
Text mining of scientific libraries and social media has already proven itself as a reliable tool for drug repurposing and hypothesis generation. The task of mapping a disease mention to a concept in a controlled vocabulary, typically to the standard...

Unsupervised Bayesian Inference to Fuse Biosignal Sensory Estimates for Personalizing Care.

IEEE journal of biomedical and health informatics
The role of sensing technologies, such as wearables, in delivering precision care is becoming widely acceptable. Given the very large quantities of sensor data that rapidly accumulate, there is a need to employ automated algorithms to label biosignal...

Approaches to Medical Decision-Making Based on Big Clinical Data.

Journal of healthcare engineering
The paper discusses different approaches to building a medical decision support system based on big data. The authors sought to abstain from any data reduction and apply universal teaching and big data processing methods independent of disease classi...

A rank weighted classification for plasma proteomic profiles based on case-based reasoning.

BMC medical informatics and decision making
BACKGROUND: It is a challenge to precisely classify plasma proteomic profiles into their clinical status based solely on their patterns even though distinct patterns of plasma proteomic profiles are regarded as potential to be a biomarker because the...

Simulation of patient flow in multiple healthcare units using process and data mining techniques for model identification.

Journal of biomedical informatics
INTRODUCTION: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic methods for comb...