AIMC Topic: Melanoma

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GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure.

PloS one
Neoantigens are tumor-derived peptides and are biomarkers that can predict prognosis related to immune checkpoint inhibition by estimating their binding to major histocompatibility complex (MHC) proteins. Although deep neural networks have been prima...

Optimizing time prediction and error classification in early melanoma detection using a hybrid RCNN-LSTM model.

Microscopy research and technique
Skin cancer is a terrifying disorder that affects all individuals. Due to the significant increase in the rate of melanoma skin cancer, early detection of skin cancer is now more critical than ever before. Malignant melanoma is one of the most seriou...

Enhancing skin lesion classification with advanced deep learning ensemble models: a path towards accurate medical diagnostics.

Current problems in cancer
Skin cancer, including the highly lethal malignant melanoma, poses a significant global health challenge with a rising incidence rate. Early detection plays a pivotal role in improving survival rates. This study aims to develop an advanced deep learn...

Patient and dermatologists' perspectives on augmented intelligence for melanoma screening: A prospective study.

Journal of the European Academy of Dermatology and Venereology : JEADV
BACKGROUND: Artificial intelligence (AI) shows promising potential to enhance human decision-making as synergistic augmented intelligence (AuI), but requires critical evaluation for skin cancer screening in a real-world setting.

Machine learning developed an intratumor heterogeneity signature for predicting prognosis and immunotherapy benefits in skin cutaneous melanoma.

Melanoma research
Intratumor heterogeneity (ITH) is defined as differences in molecular and phenotypic profiles between different tumor cells and immune cells within a tumor. ITH was involved in the cancer progression, aggressiveness, therapy resistance and cancer rec...

Fusion between an Algorithm Based on the Characterization of Melanocytic Lesions' Asymmetry with an Ensemble of Convolutional Neural Networks for Melanoma Detection.

The Journal of investigative dermatology
Melanoma is still a major health problem worldwide. Early diagnosis is the first step toward reducing its mortality, but it remains a challenge even for experienced dermatologists. Although computer-aided systems have been developed to help diagnosis...

Evaluating deep learning-based melanoma classification using immunohistochemistry and routine histology: A three center study.

PloS one
Pathologists routinely use immunohistochemical (IHC)-stained tissue slides against MelanA in addition to hematoxylin and eosin (H&E)-stained slides to improve their accuracy in diagnosing melanomas. The use of diagnostic Deep Learning (DL)-based supp...