AIMC Topic: Microscopy, Phase-Contrast

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Cell mitosis event analysis in phase contrast microscopy images using deep learning.

Medical image analysis
In this paper, we solve the problem of mitosis event localization and its stage localization in time-lapse phase-contrast microscopy images. Our method contains three steps: first, we formulate a Low-Rank Matrix Recovery (LRMR) model to find salient ...

Automated Classification of Apoptosis in Phase Contrast Microscopy Using Capsule Network.

IEEE transactions on medical imaging
Automatic and accurate classification of apoptosis, or programmed cell death, will facilitate cell biology research. The state-of-the-art approaches in apoptosis classification use deep convolutional neural networks (CNNs). However, these networks ar...

Reagent-Free and Rapid Assessment of T Cell Activation State Using Diffraction Phase Microscopy and Deep Learning.

Analytical chemistry
CD8 T cells constitute an essential compartment of the adaptive immune system. During immune responses, naı̈ve T cells become functional, as they are primed with their cognate determinants by the antigen presenting cells. Current methods of identifyi...

A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones.

Cancer research
: Artificial intelligence (AI) trained with a convolutional neural network (CNN) is a recent technological advancement. Previously, several attempts have been made to train AI using medical images for clinical applications. However, whether AI can di...

Using machine-learning to optimize phase contrast in a low-cost cellphone microscope.

PloS one
Cellphones equipped with high-quality cameras and powerful CPUs as well as GPUs are widespread. This opens new prospects to use such existing computational and imaging resources to perform medical diagnosis in developing countries at a very low cost....

Colony analysis and deep learning uncover 5-hydroxyindole as an inhibitor of gliding motility and iridescence in Cellulophaga lytica.

Microbiology (Reading, England)
Iridescence is an original type of colouration that is relatively widespread in nature but has been either incompletely described or entirely neglected in prokaryotes. Recently, we reported a brilliant 'pointillistic' iridescence in agar-grown colony...

Detection and Recognition for Life State of Cell Cancer Using Two-Stage Cascade CNNs.

IEEE/ACM transactions on computational biology and bioinformatics
Cancer cell detection and its stages recognition of life cycle are an important step to analyze cellular dynamics in the automation of cell based-experiments. In this work, a two-stage hierarchical method is proposed to detect and recognize different...

Phase contrast cell detection using multilevel classification.

International journal for numerical methods in biomedical engineering
In this paper, we propose a fully automated learning-based approach for detecting cells in time-lapse phase contrast images. The proposed system combines 2 machine learning approaches to achieve bottom-up image segmentation. We apply pixel-wise class...

Towards Fluorescent-Tag-Less Viral Titration: Automated Estimation of Cell-Size Distribution and Infection Level from Phase-Contrast Microscopy Using Deep Learning and Transfer Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Automated detection of infected insect cells is one of the crucial tasks in the field of recombinant protein production and vaccine development. The major challenge lies in manual segmentation of cells and quantifying cell size distribution is tediou...

Rapid fiber-detection technique by artificial intelligence in phase-contrast microscope images of simulated atmospheric samples.

Annals of work exposures and health
Since the manufacture, import, and use of asbestos products have been completely abolished in Japan, the main cause of asbestos emissions into the atmosphere is the demolition and removal of buildings built with asbestos-containing materials. To dete...