AIMC Topic: Microscopy

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Collagen fiber centerline tracking in fibrotic tissue via deep neural networks with variational autoencoder-based synthetic training data generation.

Medical image analysis
The role of fibrillar collagen in the tissue microenvironment is critical in disease contexts ranging from cancers to chronic inflammations, as evidenced by many studies. Quantifying fibrillar collagen organization has become a powerful approach for ...

Parasitic egg recognition using convolution and attention network.

Scientific reports
Intestinal parasitic infections (IPIs) caused by protozoan and helminth parasites are among the most common infections in humans in low-and-middle-income countries. IPIs affect not only the health status of a country, but also the economic sector. Ov...

iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays.

Nature communications
While microscopy-based cellular assays, including microfluidics, have significantly advanced over the last several decades, there has not been concurrent development of widely-accessible techniques to analyze time-dependent microscopy data incorporat...

DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning.

Nature methods
Single-molecule localization microscopy (SMLM) has revolutionized biological imaging, improving the spatial resolution of traditional microscopes by an order of magnitude. However, SMLM techniques require long acquisition times, typically a few minut...

Digital pathology systems enabling quality patient care.

Genes, chromosomes & cancer
Pathology laboratories are undergoing digital transformations, adopting innovative technologies to enhance patient care. Digital pathology systems impact clinical, education, and research use cases where pathologists use digital technologies to perfo...

Whole Slide Imaging Technology and Its Applications: Current and Emerging Perspectives.

International journal of surgical pathology
. Whole slide imaging (WSI) represents a paradigm shift in pathology, serving as a necessary first step for a wide array of digital tools to enter the field. It utilizes virtual microscopy wherein glass slides are converted into digital slides and ar...

WormSwin: Instance segmentation of C. elegans using vision transformer.

Scientific reports
The possibility to extract motion of a single organism from video recordings at a large-scale provides means for the quantitative study of its behavior, both individual and collective. This task is particularly difficult for organisms that interact w...

AutoFibroNet: A deep learning and multi-photon microscopy-derived automated network for liver fibrosis quantification in MAFLD.

Alimentary pharmacology & therapeutics
BACKGROUND: Liver fibrosis is the strongest histological risk factor for liver-related complications and mortality in metabolic dysfunction-associated fatty liver disease (MAFLD). Second harmonic generation/two-photon excitation fluorescence (SHG/TPE...

DeXtrusion: automatic recognition of epithelial cell extrusion through machine learning in vivo.

Development (Cambridge, England)
Accurately counting and localising cellular events from movies is an important bottleneck of high-content tissue/embryo live imaging. Here, we propose a new methodology based on deep learning that allows automatic detection of cellular events and the...

Ultrasound Localization Microscopy Using Deep Neural Network.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Noninvasive imaging of microvascular structures in deep tissues provides morphological and functional information for clinical diagnosis and monitoring. Ultrasound localization microscopy (ULM) is an emerging imaging technique that can generate micro...