AIMC Topic: Multiple Sclerosis

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Artificial intelligence applied to MRI data to tackle key challenges in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)
Artificial intelligence (AI) is the branch of science aiming at creating algorithms able to carry out tasks that typically require human intelligence. In medicine, there has been a tremendous increase in AI applications thanks to increasingly powerfu...

The diagnostic performance of AI-based algorithms to discriminate between NMOSD and MS using MRI features: A systematic review and meta-analysis.

Multiple sclerosis and related disorders
BACKGROUND: Magnetic resonance imaging [MRI] findings in Neuromyelitis optica spectrum disorder [NMOSD] and Multiple Sclerosis [MS] patients could lead us to discriminate toward them. For instance, U-fiber and Dawson's finger-type lesions are suggest...

Improving the classification of multiple sclerosis and cerebral small vessel disease with interpretable transfer attention neural network.

Computers in biology and medicine
As an autoimmune-mediated inflammatory demyelinating disease of the central nervous system, multiple sclerosis (MS) is often confused with cerebral small vessel disease (cSVD), which is a regional pathological change in brain tissue with unknown path...

LST-AI: A deep learning ensemble for accurate MS lesion segmentation.

NeuroImage. Clinical
Automated segmentation of brain white matter lesions is crucial for both clinical assessment and scientific research in multiple sclerosis (MS). Over a decade ago, we introduced an engineered lesion segmentation tool, LST. While recent lesion segment...

Deep learning for discrimination of active and inactive lesions in multiple sclerosis using non-contrast FLAIR MRI: A multicenter study.

Multiple sclerosis and related disorders
BACKGROUND: Within the domain of multiple sclerosis (MS), the precise discrimination between active and inactive lesions bears immense significance. Active lesions are enhanced on T1-weighted MRI images after administration of gadolinium-based contra...

Improving multiple sclerosis lesion segmentation across clinical sites: A federated learning approach with noise-resilient training.

Artificial intelligence in medicine
Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise for automati...

Robotic assisted and exoskeleton gait training effect in mental health and fatigue of multiple sclerosis patients. A systematic review and a meta-analysis.

Disability and rehabilitation
PURPOSE: Robotic and Exoskeleton Assisted Gait Training (REAGT) has become the mainstream gait training module. Studies are investigating the psychosocial effects of REAGT mostly as secondary outcomes. Our systematic review and meta-analysis aims to ...

Spinet-QSM: model-based deep learning with schatten p-norm regularization for improved quantitative susceptibility mapping.

Magma (New York, N.Y.)
OBJECTIVE: Quantitative susceptibility mapping (QSM) provides an estimate of the magnetic susceptibility of tissue using magnetic resonance (MR) phase measurements. The tissue magnetic susceptibility (source) from the measured magnetic field distribu...

Predicting the conversion from clinically isolated syndrome to multiple sclerosis: An explainable machine learning approach.

Multiple sclerosis and related disorders
INTRODUCTION: Predicting the conversion of clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS) is critical to personalizing treatment planning and benefits for patients. The aim of this study is to develop an explainab...

Artificial intelligence in multiple sclerosis management: Challenges in a new era.

Multiple sclerosis and related disorders
Multiple sclerosis poses diagnostic and therapeutic challenges for healthcare professionals, with a high risk of misdiagnosis and difficulties in assessing therapeutic effectiveness. Artificial intelligence, particularly machine learning and deep neu...