Prostate cancer is the most common and second most deadly form of cancer in men in the United States. The classification of prostate cancers based on Gleason grading using histological images is important in risk assessment and treatment planning for...
RNA-protein interaction (RPI) plays an important role in the basic cellular processes of organisms. Unfortunately, due to time and cost constraints, it is difficult for biological experiments to determine the relationship between RNA and protein to a...
OBJECTIVE: A novel computer-aided detection (CAD) scheme for lung nodule detection using a 3D deep convolutional neural network combined with a multi-scale prediction strategy is proposed to assist radiologists by providing a second opinion on accura...
Deep neural networks (DNNs) trained in a supervised way suffer from two known problems. First, the minima of the objective function used in learning correspond to data points (also known as rubbish examples or fooling images) that lack semantic simil...
We describe a simple method to transfer from weights in deep neural networks (NNs) trained by a deep belief network (DBN) to weights in a backpropagation NN (BPNN) in the recursive-rule eXtraction (Re-RX) algorithm with J48graft (Re-RX with J48graft)...
Computer methods and programs in biomedicine
Oct 12, 2018
BACKGROUND AND OBJECTIVE: In healthcare systems, the cost of unplanned readmission accounts for a large proportion of total hospital payment. Hospital-specific readmission rate becomes a critical issue around the world. Quantification and early ident...
Proceedings of the National Academy of Sciences of the United States of America
Oct 12, 2018
Humans and most animals can learn new tasks without forgetting old ones. However, training artificial neural networks (ANNs) on new tasks typically causes them to forget previously learned tasks. This phenomenon is the result of "catastrophic forgett...
Empirical data from a 6-month mesocosms experiment were used to assess the ability and performance of two machine learning (ML) models, including artificial neural network (NN) and random forest (RF), to predict temporal bioavailability changes of co...
We present a molecular dynamics simulation study of alkali metal cation transport through the double-helical and the head-to-head conformers of the gramicidin ion channel. Our approach is based on a thermodynamic integration network, which consists o...
In the past two decades, significant advances have been made on automated electroencephalogram (EEG)-based diagnosis of epilepsy and seizure detection. A number of innovative algorithms have been introduced that can aid in epilepsy diagnosis with a h...
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