MOTIVATION: Identifying compound-protein interaction (CPI) is a crucial task in drug discovery and chemogenomics studies, and proteins without three-dimensional structure account for a large part of potential biological targets, which requires develo...
Mathematical biosciences and engineering : MBE
Aug 12, 2020
Despite the increasing use of technology, handwriting has remained to date as an efficient means of communication. Certainly, handwriting is a critical motor skill for childrens cognitive development and academic success. This article presents a new ...
Safe and efficient use of ultrasmall nanoparticles (NPs) in biomedicine requires numerous independent conditions to be met, including colloidal stability, selectivity for proteins and membranes, binding specificity, and low affinity for plasma protei...
Different techniques exist for determining chlorophyll-a concentration as a proxy of phytoplankton abundance. In this study, a novel method based on the spectral particulate beam-attenuation coefficient (c) was developed to estimate chlorophyll-a con...
We describe and compare two machine learning approaches for cell classification based on label-free quantitative phase imaging with transport of intensity equation methods. In one approach, we design a multilevel integrated machine learning classifie...
We systematically study the percolation phase transition at the change of concentration of the chaotic defects (pores) in an extended system where the disordered defects additionally have a variable random radius, using the methods of a neural networ...
SIGNIFICANCE: Two-dimensional (2-D) fully convolutional neural networks have been shown capable of producing maps of sO2 from 2-D simulated images of simple tissue models. However, their potential to produce accurate estimates in vivo is uncertain as...
Representation learning on networks offers a powerful alternative to the oft painstaking process of manual feature engineering, and, as a result, has enjoyed considerable success in recent years. However, all the existing representation learning meth...
Computer vision systems (CVS) have been shown to be a powerful tool for the measurement of live pig body weight (BW) with no animal stress. With advances in precision farming, it is now possible to evaluate the growth performance of individual pigs m...
A drug-drug interaction or drug synergy is extensively utilised for cancer treatment. However, prediction of drug-drug interaction is defined as an ill-posed problem, because manual testing is only implementable on small group of drugs. Predicting th...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.