AIMC Topic: Phthalimides

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A tri-functional probe mediated exponential amplification strategy for highly sensitive detection of Dnmt1 and UDG activities at single-cell level.

Analytica chimica acta Dec 23, 2019
Multiplex DNA methylation and glycosylation are ubiquitous in the human body to ensure the normal function and stability of the genome. The methyltransferases and glycosylases rely on varied enzymes with different action mechanism, which still remain...
Humans Cell Line, Tumor Single-Cell Analysis Nucleic Acid Amplification Techniques Limit of Detection DNA (Cytosine-5-)-Methyltransferase 1 DNA Probes DNA, Single-Stranded Enzyme Assays Nucleic Acid Hybridization Phthalimides Tryptophan Uracil-DNA Glycosidase
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Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.

Oxidative medicine and cellular longevity Dec 18, 2018
Postcardiac arrest syndrome yields poor neurological outcomes, but the mechanisms underlying this condition remain poorly understood. Autophagy plays an important role in neuronal apoptosis induced by ischemia. However, whether autophagy is involved ...
Cells, Cultured Animals Male Oxidative Stress Mice Disease Models, Animal Apoptosis Mice, Inbred C57BL Reperfusion Injury Astrocytes Autophagy Neurons Phthalimides Ischemic Attack, Transient Microtubule-Associated Proteins Quinolines Transient Receptor Potential Channels
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