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Optic Nerve Diseases

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Individualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest.

Translational vision science & technology
PURPOSE: To compare change over time in eye-specific optical coherence tomography (OCT) retinal nerve fiber layer (RNFL)-based region-of-interest (ROI) maps developed using unsupervised deep-learning auto-encoders (DL-AE) to circumpapillary RNFL (cpR...

Discriminating glaucomatous and compressive optic neuropathy on spectral-domain optical coherence tomography with deep learning classifier.

The British journal of ophthalmology
BACKGROUND/AIMS: To assess the performance of a deep learning classifier for differentiation of glaucomatous optic neuropathy (GON) from compressive optic neuropathy (CON) based on ganglion cell-inner plexiform layer (GCIPL) and retinal nerve fibre l...

Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems.

American journal of ophthalmology
PURPOSE: We sought to assess the performance of deep learning approaches for differentiating nonglaucomatous optic neuropathy with disc pallor (NGON) vs glaucomatous optic neuropathy (GON) on color fundus photographs by the use of image recognition.

Deep Learning and Transfer Learning for Optic Disc Laterality Detection: Implications for Machine Learning in Neuro-Ophthalmology.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
BACKGROUND: Deep learning (DL) has demonstrated human expert levels of performance for medical image classification in a wide array of medical fields, including ophthalmology. In this article, we present the results of our DL system designed to deter...

AxoNet: A deep learning-based tool to count retinal ganglion cell axons.

Scientific reports
In this work, we develop a robust, extensible tool to automatically and accurately count retinal ganglion cell axons in optic nerve (ON) tissue images from various animal models of glaucoma. We adapted deep learning to regress pixelwise axon count de...

Deep learning-based automated detection of glaucomatous optic neuropathy on color fundus photographs.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
PURPOSE: To develop a deep learning approach based on deep residual neural network (ResNet101) for the automated detection of glaucomatous optic neuropathy (GON) using color fundus images, understand the process by which the model makes predictions, ...

Deep Learning Approaches Predict Glaucomatous Visual Field Damage from OCT Optic Nerve Head En Face Images and Retinal Nerve Fiber Layer Thickness Maps.

Ophthalmology
PURPOSE: To develop and evaluate a deep learning system for differentiating between eyes with and without glaucomatous visual field damage (GVFD) and predicting the severity of GFVD from spectral domain OCT (SD OCT) optic nerve head images.