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Optical Imaging

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Red blood cell classification in lensless single random phase encoding using convolutional neural networks.

Optics express
Rapid cell identification is achieved in a compact and field-portable system employing single random phase encoding to record opto-biological signatures of living biological cells of interest. The lensless, 3D-printed system uses a diffuser to encode...

Virtual organelle self-coding for fluorescence imaging via adversarial learning.

Journal of biomedical optics
SIGNIFICANCE: Our study introduces an application of deep learning to virtually generate fluorescence images to reduce the burdens of cost and time from considerable effort in sample preparation related to chemical fixation and staining.

Biohybrid robotics with living cell actuation.

Chemical Society reviews
As simulators of organisms in Nature, soft robots have been developed over the past few decades. In particular, biohybrid robots constructed by integrating living cells with soft materials demonstrate the unique advantage of simulating the constructi...

Implementing machine learning methods for imaging flow cytometry.

Microscopy (Oxford, England)
In this review, we focus on the applications of machine learning methods for analyzing image data acquired in imaging flow cytometry technologies. We propose that the analysis approaches can be categorized into two groups based on the type of data, r...

A new method using machine learning for automated image analysis applied to chip-based digital assays.

The Analyst
Chip-based digital assays such as the digital polymerase chain reaction (digital PCR), digital loop-mediated amplification (digital LAMP), digital enzyme-linked immunosorbent assay (digital ELISA) and digital proximity ligation assay (digital PLA) ne...

Burn wound classification model using spatial frequency-domain imaging and machine learning.

Journal of biomedical optics
Accurate assessment of burn severity is critical for wound care and the course of treatment. Delays in classification translate to delays in burn management, increasing the risk of scarring and infection. To this end, numerous imaging techniques have...

Optical biopsy of head and neck cancer using hyperspectral imaging and convolutional neural networks.

Journal of biomedical optics
For patients undergoing surgical cancer resection of squamous cell carcinoma (SCCa), cancer-free surgical margins are essential for good prognosis. We developed a method to use hyperspectral imaging (HSI), a noncontact optical imaging modality, and c...

Machine learning approach for rapid and accurate estimation of optical properties using spatial frequency domain imaging.

Journal of biomedical optics
Fast estimation of optical properties from reflectance measurements at two spatial frequencies could pave way for real-time, wide-field and quantitative mapping of vital signs of tissues. We present a machine learning-based approach for estimating op...

Deep learning model for ultrafast multifrequency optical property extractions for spatial frequency domain imaging.

Optics letters
Spatial frequency domain imaging (SFDI) is emerging as an important new method in biomedical imaging due to its ability to provide label-free, wide-field tissue optical property maps. Most prior SFDI studies have utilized two spatial frequencies (2-f...