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Organs at Risk

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Patient selection for proton therapy using Normal Tissue Complication Probability with deep learning dose prediction for oropharyngeal cancer.

Medical physics
BACKGROUND: In cancer care, determining the most beneficial treatment technique is a key decision affecting the patient's survival and quality of life. Patient selection for proton therapy (PT) over conventional radiotherapy (XT) currently entails co...

A comparative study of deep learning-based knowledge-based planning methods for 3D dose distribution prediction of head and neck.

Journal of applied clinical medical physics
PURPOSE: In this paper, we compare four novel knowledge-based planning (KBP) algorithms using deep learning to predict three-dimensional (3D) dose distributions of head and neck plans using the same patients' dataset and quantitative assessment metri...

First Report On Physician Assessment and Clinical Acceptability of Custom-Retrained Artificial Intelligence Models for Clinical Target Volume and Organs-at-Risk Auto-Delineation for Postprostatectomy Patients.

Practical radiation oncology
PURPOSE: To assess the clinical acceptability of a commercial deep-learning-based auto-segmentation (DLAS) prostate model that was retrained using institutional data for delineation of the clinical target volume (CTV) and organs-at-risk (OARs) for po...

Geometric and dosimetric evaluation of deep learning based auto-segmentation for clinical target volume on breast cancer.

Journal of applied clinical medical physics
BACKGROUND: Recently, target auto-segmentation techniques based on deep learning (DL) have shown promising results. However, inaccurate target delineation will directly affect the treatment planning dose distribution and the effect of subsequent radi...

Validation of a Fully Automated Hybrid Deep Learning Cardiac Substructure Segmentation Tool for Contouring and Dose Evaluation in Lung Cancer Radiotherapy.

Clinical oncology (Royal College of Radiologists (Great Britain))
BACKGROUND AND PURPOSE: Accurate and consistent delineation of cardiac substructures is challenging. The aim of this work was to validate a novel segmentation tool for automatic delineation of cardiac structures and subsequent dose evaluation, with p...

Artificial intelligence-supported applications in head and neck cancer radiotherapy treatment planning and dose optimisation.

Radiography (London, England : 1995)
INTRODUCTION: The aim of this review is to describe how various AI-supported applications are used in head and neck cancer radiotherapy treatment planning, and the impact on dose management in regards to target volume and nearby organs at risk (OARs)...

TrDosePred: A deep learning dose prediction algorithm based on transformers for head and neck cancer radiotherapy.

Journal of applied clinical medical physics
BACKGROUND: Intensity-Modulated Radiation Therapy (IMRT) has been the standard of care for many types of tumors. However, treatment planning for IMRT is a time-consuming and labor-intensive process.

Contouring quality assurance methodology based on multiple geometric features against deep learning auto-segmentation.

Medical physics
BACKGROUND: Contouring error is one of the top failure modes in radiation treatment. Multiple efforts have been made to develop tools to automatically detect segmentation errors. Deep learning-based auto-segmentation (DLAS) has been used as a baselin...

Evaluation of auto-segmentation for brachytherapy of postoperative cervical cancer using deep learning-based workflow.

Physics in medicine and biology
. The purpose of this study was to evaluate the accuracy of brachytherapy (BT) planning structures derived from Deep learning (DL) based auto-segmentation compared with standard manual delineation for postoperative cervical cancer.. We introduced a c...

Segmentation of multiple Organs-at-Risk associated with brain tumors based on coarse-to-fine stratified networks.

Medical physics
BACKGROUND: Delineation of Organs-at-Risks (OARs) is an important step in radiotherapy treatment planning. As manual delineation is time-consuming, labor-intensive and affected by inter- and intra-observer variability, a robust and efficient automati...