OBJECTIVE: Conventional methodologies are ineffective in predicting the rapid progression of knee osteoarthritis (OA). MicroRNAs (miRNAs) show promise as biomarkers for patient stratification. We aimed to develop a miRNA prognosis model for identifyi...
BACKGROUND: Poor results occasionally occur after unicompartmental knee replacement (UKR). It is often difficult, even for experienced surgeons, to determine why patients have poor outcomes from radiographs. The aim was to compare the ability of expe...
Osteochondral interface consists of two tissues: the calcified cartilage (CC) containing chondrocytes, and subchondral bone (SCB) containing osteocytes that interact with each other. In this study, we propose a new method for the three-dimensional (3...
Journal of orthopaedic surgery and research
39568048
BACKGROUND: Accurate measurement of the hip-knee-ankle (HKA) angle is essential for informed clinical decision-making in the management of knee osteoarthritis (OA). Knee OA is commonly associated with varus deformity, where the alignment of the knee ...
Knee osteoarthritis (KOA) combined with depressive symptoms is prevalent and leads to poor outcomes and significant financial burdens. However, practical tools for identifying at-risk patients remain limited. A robust prediction model is needed to ad...
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
39557015
Having osteoarthritis in one knee is reported as an independent risk factor for developing contralateral knee osteoarthritis (KOA). However, no study has been designed to predict the development of contralateral KOA (cKOA). The authors hypothesized t...
Knee osteoarthritis (KOA) represents a well-documented degenerative arthropathy prevalent among the elderly population. KOA is a persistent condition, also referred to as progressive joint Disease, stemming from the continual deterioration of cartila...
Journal of orthopaedic surgery and research
39702314
BACKGROUND: Osteoarthritis (OA) of the knee is a prevalent chronic degenerative joint condition that is having a growing impact on a global scale., posing a challenge in diagnosis which is often reliant on time-consuming and error-prone visual analys...
OBJECTIVE: To use routine demographic and clinical data to develop an interpretable individual-level machine learning (ML) model to diagnose knee osteoarthritis (KOA) and to identify highly ranked features.
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
39621063
INTRODUCTION: Knee osteoarthritis is one of the most prevalent and debilitating musculoskeletal diseases, with a high incidence among the elderly population. Early detection and accurate classification can improve clinical outcomes for affected patie...