Medical oncology (Northwood, London, England)
May 28, 2025
Pancreatic cancer is a highly aggressive malignancy with rising incidence and mortality rates, often diagnosed at advanced stages. Conventional imaging methods, such as computed tomography (CT) and magnetic resonance imaging (MRI), struggle to assess...
INTRODUCTION: Pancreatic cancer (PC) remains a lethal malignancy with limited treatment options. The role of innate immune cell barrier-related genes in PC prognosis is poorly defined. This study aimed to identify prognostic biomarkers, develop a pre...
International journal of molecular sciences
May 22, 2025
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options, and early detection remains challenging due to the lack of reliable non-invasive biomarkers. This study investigated plasma and urine circulating tumor deo...
Accurate and fully automated pancreas segmentation is critical for advancing imaging biomarkers in early pancreatic cancer detection and for biomarker discovery in endocrine and exocrine pancreatic diseases. We developed and evaluated a deep learning...
RATIONALE AND OBJECTIVES: Accurate risk stratification is critical for guiding personalized treatment in resectable pancreatic cancer (RPC). This retrospective study assessed the utility of habitat radiomics for predicting recurrence-free survival (R...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
May 1, 2025
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC), known for its high fatality rate, is often diagnosed in its advanced stages where surgical options are not viable. This highlights the critical need for innovative and effective early detection techni...
Raman spectroscopy, as a label-free optical technique, provides a unique solution for tissue diagnosis. However, due to the limitation of point-by-point acquisition mode and multivariate statistical analysis methods, conventional methods pose a major...
The malignant potential of pancreatic cystic lesions (PCLs) varies dramatically, leading to difficulties when making clinical decisions. This study aimed to develop noninvasive clinical-radiomic models using preoperative CT images to predict the mali...
INTRODUCTION: About 25% of patients undergoing pancreaticoduodenectomy (PD) for right-sided pancreatic ductal adenocarcinoma (PDAC) die within 1 y of diagnosis. These patients carry all the risks of significant morbidity with no survival advantage wh...
Despite the strides made in medical science, pancreatic cancer continues to be a threat, highlighting the urgent need for creative strategies to address this concern. Recently, a potential approach that has attracted significant attention is using ma...
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