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Parabens

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Combination of large volume sample stacking with polarity switching and cyclodextrin electrokinetic chromatography (LVSS-PS-CDEKC) for the determination of selected preservatives in pharmaceuticals.

Talanta
In this study, a large volume sample stacking (LVSS) with polarity switching (PS) and cyclodextrin electrokinetic chromatography (CDEKC) method has been developed for the simultaneous separation and determination of 8 preservatives: methylparaben (MP...

Accurate analysis of parabens in human urine using isotope-dilution ultrahigh-performance liquid chromatography-high resolution mass spectrometry.

Journal of pharmaceutical and biomedical analysis
An analytical method that utilizes isotope-dilution ultrahigh-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS or called UHPLC-HRMS) was developed, and validated to be highly precise and...

Investigation of genotoxic effects of paraben in cultured human lymphocytes.

Drug and chemical toxicology
Paraben is a phenolic derivative of benzoic acid extensively used as preservatives in food, pharmaceutical, and cosmetic industries due to its antimicrobial characteristics. The objective of this study was to evaluate the in vitro genotoxic effects o...

Maternal urinary paraben levels and offspring size at birth from a Chinese birth cohort.

Chemosphere
BACKGROUND: Parabens are suspected to impair fetal growth because of their endocrine disrupting effects. Epidemiological studies regarding the effects of prenatal exposure to parabens on birth outcomes are limited.

Determination of parabens in wastewater samples via robot-assisted dynamic single-drop microextraction and liquid chromatography-tandem mass spectrometry.

Electrophoresis
Dynamic single-drop microextraction (SDME) was automatized employing an Arduino-based lab-made Cartesian robot and implemented to determine parabens in wastewater samples in combination with liquid chromatography-tandem mass spectrometry. A dedicated...

Unveiling the effect of urinary xenoestrogens on chronic kidney disease in adults: A machine learning model.

Ecotoxicology and environmental safety
Exposure to three primary xenoestrogens (XEs), including phthalates, parabens, and phenols, has been strongly associated with chronic kidney disease (CKD). An interpretable machine learning (ML) model was developed to predict CKD using data from the ...