PD (Parkinson's Disease) is a severe malady that is painful and incurable, affecting older human beings. Identifying PD early in a precise manner is critical for the lengthened survival of patients, where DMTs (data mining techniques) and MLTs (machi...
Drug discovery for diseases such as Parkinson's disease are impeded by the lack of screenable cellular phenotypes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and dee...
BACKGROUND: Parkinson's disease (PD) is a neurological disorder that is marked by the deficit of neurons in the midbrain that changes motor and cognitive function. In the substantia nigra, the selective demise of dopamine-producing neurons was the ma...
The diagnostic performance of a combined architecture on Parkinson's disease using diffusion tensor imaging was evaluated. A convolutional neural network was trained from multiple parcellated brain regions. A greedy algorithm was proposed to combine ...
International journal of environmental research and public health
Feb 24, 2022
(1) Background: Parkinson's Disease (PD) is one of the most common causes of disability among older individuals. The advanced stages of PD are usually characterized by postural instability and, as a consequence, falls. Those are among the main factor...
Parkinson's disease (PD) is one of the most serious and challenging neurodegenerative disorders to diagnose. Clinical diagnosis on observing motor symptoms is the gold standard, yet by this point nerve cells are degenerated resulting in a lower effic...
Annals of physical and rehabilitation medicine
Feb 23, 2022
BACKGROUND: Robot-assisted gait training (RAGT) may have beneficial effects on Parkinson's disease (PD); however, the evidence to date is inconsistent.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Feb 21, 2022
Deep brain stimulation is a complex movement disorder intervention that requires highly invasive brain surgery. Clinicians struggle to predict how patients will respond to this treatment. To address this problem, we are working toward developing a cl...
The diagnosis of Parkinson's disease (PD) is challenging at all stages due to variable symptomatology, comorbidities, and mimicking conditions. Postmortem assessment remains the gold standard for a definitive diagnosis. While it is well recognized th...
Movement disorders : official journal of the Movement Disorder Society
Feb 1, 2022
BACKGROUND: Isolated REM sleep behavior disorder (iRBD) is considered a prodromal stage of parkinsonism. Neurodegenerative changes in the substantia nigra pars compacta (SNc) in parkinsonism can be detected using neuromelanin-sensitive MRI.