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Positron-Emission Tomography

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Improved myocardial perfusion PET imaging using artificial neural networks.

Physics in medicine and biology
Myocardial perfusion (MP) PET imaging plays a key role in risk assessment and stratification of patients with coronary artery disease. In this work, we proposed a patch-based artificial neural network (ANN) fusion approach that integrates information...

Reinventing radiation therapy with machine learning and imaging bio-markers (radiomics): State-of-the-art, challenges and perspectives.

Methods (San Diego, Calif.)
Radiation therapy is a pivotal cancer treatment that has significantly progressed over the last decade due to numerous technological breakthroughs. Imaging is now playing a critical role on deployment of the clinical workflow, both for treatment plan...

Feasibility of Multiparametric Positron Emission Tomography/Magnetic Resonance Imaging as a One-Stop Shop for Radiation Therapy Planning for Patients with Head and Neck Cancer.

International journal of radiation oncology, biology, physics
PURPOSE: Multiparametric positron emission tomography (PET)/magnetic resonance imaging (MRI) as a one-stop shop for radiation therapy (RT) planning has great potential but is technically challenging. We studied the feasibility of performing multipara...

Predicting PET Cerebrovascular Reserve with Deep Learning by Using Baseline MRI: A Pilot Investigation of a Drug-Free Brain Stress Test.

Radiology
Background Cerebrovascular reserve (CVR) may be measured by using an acetazolamide test to clinically evaluate patients with cerebrovascular disease. However, acetazolamide use may be contraindicated and/or undesirable in certain clinical settings. P...

Investigating the challenges and generalizability of deep learning brain conductivity mapping.

Physics in medicine and biology
To investigate deep learning electrical properties tomography (EPT) for application on different simulated and in-vivo datasets, including pathologies for brain conductivity reconstructions, 3D patch-based convolutional neural networks were trained t...

Generative adversarial network based regularized image reconstruction for PET.

Physics in medicine and biology
Positron emission tomography (PET) is an ill-posed inverse problem and suffers high noise due to limited number of detected events. Prior information can be used to improve the quality of reconstructed PET images. Deep neural networks have also been ...

Positron emission tomography imaging in cardiovascular disease.

Heart (British Cardiac Society)
Positron emission tomography (PET) imaging is useful in cardiovascular disease across several areas, from assessment of myocardial perfusion and viability, to highlighting atherosclerotic plaque activity and measuring the extent of cardiac innervatio...

Deep learning detection of prostate cancer recurrence with F-FACBC (fluciclovine, Axumin®) positron emission tomography.

European journal of nuclear medicine and molecular imaging
PURPOSE: To evaluate the performance of deep learning (DL) classifiers in discriminating normal and abnormal F-FACBC (fluciclovine, Axumin®) PET scans based on the presence of tumor recurrence and/or metastases in patients with prostate cancer (PC) a...

Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning.

European journal of nuclear medicine and molecular imaging
PURPOSE: We aimed to evaluate the performance of deep learning-based generalization of ultra-low-count amyloid PET/MRI enhancement when applied to studies acquired with different scanning hardware and protocols.

Deep-Learning F-FDG Uptake Classification Enables Total Metabolic Tumor Volume Estimation in Diffuse Large B-Cell Lymphoma.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Total metabolic tumor volume (TMTV), calculated from F-FDG PET/CT baseline studies, is a prognostic factor in diffuse large B-cell lymphoma (DLBCL) whose measurement requires the segmentation of all malignant foci throughout the body. No consensus cu...