AIMC Topic: Positron-Emission Tomography

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Recent Advances in Imaging of Preclinical, Sporadic, and Autosomal Dominant Alzheimer's Disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Observing Alzheimer's disease (AD) pathological changes in vivo with neuroimaging provides invaluable opportunities to understand and predict the course of disease. Neuroimaging AD biomarkers also allow for real-time tracking of disease-modifying tre...

Convolutional neural networks for PET functional volume fully automatic segmentation: development and validation in a multi-center setting.

European journal of nuclear medicine and molecular imaging
PURPOSE: In this work, we addressed fully automatic determination of tumor functional uptake from positron emission tomography (PET) images without relying on other image modalities or additional prior constraints, in the context of multicenter image...

Emerging methods for the characterization of ischemic heart disease: ultrafast Doppler angiography, micro-CT, photon-counting CT, novel MRI and PET techniques, and artificial intelligence.

European radiology experimental
After an ischemic event, disruptive changes in the healthy myocardium may gradually develop and may ultimately turn into fibrotic scar. While these structural changes have been described by conventional imaging modalities mostly on a macroscopic scal...

Artificial neural networks for positioning of gamma interactions in monolithic PET detectors.

Physics in medicine and biology
To detect gamma rays with good spatial, timing and energy resolution while maintaining high sensitivity we need accurate and efficient algorithms to estimate the first gamma interaction position from the measured light distribution. Furthermore, mono...

The promise of artificial intelligence and deep learning in PET and SPECT imaging.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
This review sets out to discuss the foremost applications of artificial intelligence (AI), particularly deep learning (DL) algorithms, in single-photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging. To this end, ...

Quantitative PET in the 2020s: a roadmap.

Physics in medicine and biology
Positron emission tomography (PET) plays an increasingly important role in research and clinical applications, catalysed by remarkable technical advances and a growing appreciation of the need for reliable, sensitive biomarkers of human function in h...

Differentiating IDH status in human gliomas using machine learning and multiparametric MR/PET.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The purpose of this study was to develop a voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and 3,4-dihydroxy-6-[F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (PET) images using an unsuperv...

Restoration of amyloid PET images obtained with short-time data using a generative adversarial networks framework.

Scientific reports
Our purpose in this study is to evaluate the clinical feasibility of deep-learning techniques for F-18 florbetaben (FBB) positron emission tomography (PET) image reconstruction using data acquired in a short time. We reconstructed raw FBB PET data of...

Low-dose PET image noise reduction using deep learning: application to cardiac viability FDG imaging in patients with ischemic heart disease.

Physics in medicine and biology
INTRODUCTION: Cardiac [F]FDG-PET is widely used for viability testing in patients with chronic ischemic heart disease. Guidelines recommend injection of 200-350 MBq [F]FDG, however, a reduction of radiation exposure has become increasingly important,...