AIMC Topic: Potassium Channels

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Machine learning analysis of gene expression profile reveals a novel diagnostic signature for osteoporosis.

Journal of orthopaedic surgery and research Mar 15, 2021
BACKGROUND: Osteoporosis (OP) is increasingly prevalent with the aging of the world population. It is urgent to identify efficient diagnostic signatures for the clinical application.
Humans Machine Learning Osteoporosis Female Male Gene Expression Profiling Transcriptome Protein Interaction Maps RNA, Messenger Logistic Models Potassium Channels CD5 Antigens Lymphocyte Specific Protein Tyrosine Kinase p56(lck) Signaling Lymphocytic Activation Molecule Family
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Application of Machine-Learning Methods to Recognize mitoBK Channels from Different Cell Types Based on the Experimental Patch-Clamp Results.

International journal of molecular sciences Jan 15, 2021
(1) Background: In this work, we focus on the activity of large-conductance voltage- and Ca2+-activated potassium channels (BK) from the inner mitochondrial membrane (mitoBK). The characteristic electrophysiological features of the mitoBK channels ar...
Neural Networks, Computer Artificial Intelligence Machine Learning Algorithms Pregnancy Female Animals Rats, Wistar Rats Fibroblasts Kinetics Mitochondria Hippocampus Protein Conformation Endothelium Pregnancy, Animal Ion Channel Gating Patch-Clamp Techniques Large-Conductance Calcium-Activated Potassium Channels Potassium Channels
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Traditional Chinese Medicine for Anti-Arrhythmias: Mechanisms via Potassium Channels.

Basic & clinical pharmacology & toxicology Jul 1, 2025
Cardiac arrhythmia is a common life-threatening cardiovascular disorder. Potassium channels play a crucial role in cardiac electrophysiology, and their dysfunction is closely associated with the occurrence and development of arrhythmia. Traditional C...
Humans Animals Signal Transduction Medicine, Chinese Traditional Drugs, Chinese Herbal Anti-Arrhythmia Agents Arrhythmias, Cardiac Potassium Channels
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